Sentences with phrase «marker protein with»

Wiedenmann, Jörg, et al. «EosFP, a fluorescent marker protein with UV - inducible green - to - red fluorescence conversion.»

Not exact matches

For one, it would give them three specific biological markers to hone in on: The buildup of beta amyloid and tau proteins, which cause brain plaques associated with Alzheimer's, and brain nerve cell death.

Some people will feel better and manage their weight and health markers best with higher protein, higher paleo fats, lower carb choices and no sweeteners.

At the end of the study, the curcumin group had lower levels of three blood markers of inflammation, including C - reactive protein (CRP), along with lower fasting blood sugar and hemoglobin A1c (a measure of longer term blood sugar levels).5 For comparison, the placebo group had higher blood sugar levels and increased inflammation after the eight weeks.

Usefulness of maternal serum C - reactive protein with vaginal as a marker for prediction of imminent preterm delivery and chorioamnionitis in patients with preterm labor or preterm premature rupture of membranes

Usefulness of maternal serum C - reactive protein with vaginal Ureaplasma urealyticum as a marker for prediction of imminent preterm delivery and chorioamnionitis in patients with preterm labor or preterm premature rupture of membranes

The company wanted to use it as a diagnostic marker for disease: If synthetic versions of antibodies could be tagged with aequorin in the lab, then whenever they matched up with an antigen (or surface protein) of a specific pathogen in blood or tissue, the sample would glow.

Smith says her group is investigating whether PET imaging of serotonin could be a marker to detect progression of disease, whether alone or in conjunction with scans that detect the clumping protein known as amyloid that accumulates in the brains of those with Alzheimer's disease.

Sequenom is marketing its test as an add - on to current screening methods, which estimate the chance that a woman is carrying a fetus with Down's syndrome from ultrasound results and protein markers in the blood.

C. elegans with a green fluorescent protein (GFP) marker in the ASH neuron, the neuron that senses high pH.

Since the February breakthrough, PPL Therapeutics of Edinburgh, which collaborates with the Roslin Institute, has produced five lambs from fetal cells that were genetically modified to carry marker genes and genes for human proteins.

Blood stem cells in the bone marrow have been labeled with a fluorescent marker protein.

But in the 1 September issue of the Journal of Clinical Investigation, cardiologist Michael Parmacek and his colleagues at the University of Chicago describe how they deleted two genes from the common cold virus to make it unable to cause any sniffling or fever, then replaced them with a marker gene that turns out an easily detected protein and the SM22 promoter, which turns on expression of genes in smooth muscle cells that surround arteries.

During this process, immune cells flood the blood stream with proteins such as interleukin - 6 (IL - 6), a tell - tale marker of infection.

Participants with the highest adversity scores tended to have higher levels of leptin, irisin and the inflammatory marker C - reactive protein in their blood.

With each neuron containing dozens of such proteins, the set of identity markers is essentially unique.

Researchers found expectant mothers with PCOS had significantly higher markers of inflammation, including white blood cell counts and C - reactive protein.

Prototypes could detect carcinoembryonic antigen, a protein present in high levels in patients with colon or rectal cancer; ractopamine, which is an animal - feed additive banned in many countries; and thrombin, a cardiovascular disease marker.

In an effort to identify a biological marker to help guide intervention, a new study in Biological Psychiatry reports that postoperative delirium is associated with signs of inflammation — specifically elevations in the inflammatory marker C - reactive protein (CRP)-- in patients 70 years of age or older.

Smith's team labelled the virus with green fluorescent protein, and labelled some — but not all — cells with a red marker that tagged the actin.

Compared to the control group, kidney stone formers maintained higher levels of the blood marker cystatin C and higher levels of urine protein — both of which are connected with higher risk of chronic kidney disease.

In a statement put on the Web this morning, NIH reported that all 64 lines «show characteristics of stem cell morphology» and have undergone several population doublings, and most of them have demonstrated all the protein markers «known to be associated with human embryonic stem cells.»

Mice treated with the proteins had markers of healthy glial function that were missing in the untreated Down's mice.

The prostate seemed a promising target because previous studies with mice revealed that it contained cells with the same protein markers as other known stem cells, suggesting that the necessary stem cells might be relatively easy to find.

Cells with a protein marker called CD117 +, not previously associated with prostate stem cells, proliferated after castration and testosterone injection, the researchers found.

The Discher Lab has since shown that a protein on human cells called CD47 functions as a «marker of self» by interacting with a protein on the surface of macrophages called SIRPA.

The scientists also found consistent evidence of increased pro-inflammatory markers, such as C - reactive protein and tumor necrosis factor alpha, associated with PTSD.

GFP has been utilized in numerous studies as a marker protein that can track chemical reactions within living cells, along with various other uses.

But this approach overlooks another potential marker — rogue proteins — that may be driving cancer cells and also could be targeted with existing treatments.

* She combined a marker — a gene for a jellyfish protein that fluoresces green — with a DNA sequence that turns on the green fluorescent protein in the presence of thyroid hormones.

Raúl Méndez, ICREA researcher at IRB Barcelona and co-leader of the study, explains that «knowledge of the hepatic function of CPEB4 could be useful as a predictive marker for those people with variants of this protein, thus serving to prevent this condition, for example, through improvements in diet and better choice of eating times.

By comparing RNA sequencing with the Human Protein Atlas, we've also been able to identify new markers for the bile ducts that confirm the malformations that develop in patients with Alagille Syndrome.»

At a recent conference in Brussels, researchers presented that a NU - AGE Mediterranean style diet, tested in the project, significantly decreased the levels of the protein known as C - reactive protein, one of the main inflammatory marker linked with the aging process.

Rats born of hypoxic pregnancy with no vitamin C treatment showed increased thickening of the walls of the aorta — up to 170 % above normal — and molecular markers of disease, such as an increase in the heart's heat shock proteins, a signal of cardiac oxidative stress.

The scientists were thus able to transfer the genetic information from the known fluorescent protein eqFP615 into the DT40 chicken B cell line in order to produce protein variants of the new infrared marker Amrose with different spectral properties.

The scientists also found that a protein known as CD29 acts as a cell - surface marker for precursor fat cells that can generate mature cells with high energy potential, as shown by their UCP1 expression.

Dr. Utpal Pal, Professor in Veterinary Medicine, has been studying the Borrelia burgdorferi bacteria throughout his twelve years with UMD, and his work has already produced the protein marker used to identify this bacterial infection in the body.

Oligonucleotide - labeled antibodies allow integration of cellular protein and transcriptome measurements at a single - cell level, with the number of simultaneously assayed protein markers far surpassing what can be measured by cytometry - based approaches.

Confocal images of P150 dystrophic retina transplanted with hNPCctx — GDNF and double stained with antibodies against human nuclear antigen (red) and either (A) recoverin, a photoreceptor and cone bipolar cell marker (green), or (B) protein kinase Cα (PKCα), a bipolar cell marker (green).

Although the staining pattern can indicate towards a type of vesicle, there is no certainty without further validation by other methods like co-localization with typical marker proteins.

His studies have shown that Schlemm's canal (SC) which is central in ocular fluid homeostasis, hence IOP, and thus is directly relevant to glaucoma, has a novel, specialized phenotype with properties that are a blend of blood and lymphatic endothelia based on expression of marker proteins of each lineage.

The results suggest that elevated plasma levels of inflammatory biomarkers, including complement proteins, associate with polygenic risk scores in AD, further strengthening the link between genetic and biomarker disease predictors and indicating a potential role for these markers in disease prediction and patient stratification in AD.

Support to date for the existence of an hypoxic niche in marrow blood stem cells came from indirect evidence such as expression of the hypoxia protein Hif - 1 and related genes and staining with surrogate markers of hypoxia.

Mice infected with B31 - A3 and ospC7 / ospC +4 strains mounted typical and similar immune responses to OspC, P39 [used as a marker for infection in animals (22)-RSB-, and additional borrelial proteins (Fig. 4).

To reach that point, they first had to spend a decade standardizing, optimizing and scaling up their procedures, which involved using targeted antibodies to stain proteins and then looking for those markers inside healthy and cancerous tissue cells with high - resolution microscopy.

Whole grains may also cut levels of C - reactive protein, a marker of inflammation that has been linked not only with heart disease and type 2 diabetes but also problems in pregnancy such as premature birth, preeclampsia and fertility problems.

If the FDA adopts the panel's recommendation — the agency isn't required to do so, but typically does in such cases — it would mark the first time that a statin was approved for heart - disease - free people with healthy cholesterol levels but other risk factors, including high levels of C - reactive protein (CRP), a marker of inflammation.

It also appeared to lower levels of a marker of inflammation found in the blood of people with Alzheimer's (called high - sensitivity c - reactive protein)-- although it had no effect on other biomarkers of cell damage or inflammation.

A study has shown that regular consumption of small doses (20 g every 3 days) of dark chocolate is associated with lower levels of the inflammatory marker C - reactive protein.

In one recent trial, 9 a subset of patients resistant to antidepressant treatment and identified by serum markers of inflammation, most notably C - reactive protein > 3mg / L, were responsive to treatment with the TNF - alpha antagonist (anti-inflammatory) infliximab (Remicade).