Kelley and his team also used mice with fluorescent
markers in different cells of the ear followed by next generation sequencing.
Not exact matches
Once the stem
cells are created, Niklason relies on
different chemical
markers left behind
in the decellularized lungs to guide the stem
cells to their correct locations.
Accurately labelling neurons with
markers such as fluorescence, he says, will probably be the key challenge
in the eventual goal of creating a «census» of
different cell types
in the brain.
The scientists were thus able to transfer the genetic information from the known fluorescent protein eqFP615 into the DT40 chicken B
cell line
in order to produce protein variants of the new infrared
marker Amrose with
different spectral properties.
Not only were levels of metabolic compounds
different, but the expression of certain genes involved
in metabolism was turned up, and the epigenome of the
cells — molecular
markers on DNA that change gene expression on a broader scale — was altered.
Luckily,
different cell types tend to have
different things on their surfaces, which play particular parts
in their specialized roles
in the tissue, so it is a matter of identifying and targeting
cell - surface
markers that are specific to these abnormal
cell types.
Being able to image them
in the human eye at high enough resolution to use the presence of those
markers —
in this case the presence of axons and some of the shipment of
different protein cargo and other things that are important for the ganglion
cell health — to monitor those as a way to understand whether or not ganglion
cells are healthy or not or getting sicker or not.
She joined Dr. Yu's and Dr. Lichterfeld's labs
in August 2015 as a Postdoctoral Fellow to study specifically HIV reservoir (s)
in different immune
cell types using HIV nucleotide sequence diversity as
markers.
Timelapse of the internalisation of a chimeric doublet of
cells expressing an actin
marker (LifeAct)
in different colours (snapshots taken every 15 min)
We simulate the data with multivariate normal distributions, with two
different block structured covariance matrices, which only have covariance for the
marker genes
in the corresponding
cell type.
To confirm the finding, normal bone marrow
cells were exposed to either IMGN632 or X-ADC for 72 hours at a concentration highly active against AML
cells (100 pM), and the degree of caspase 3 activation, a
marker of apoptosis,
in different cell populations was assessed by flow cytometry (supplemental Figure 4).