Sentences with phrase «markers of»

«Telomeres, the protein caps on the ends of human chromosomes, are markers of aging and overall health,» said Naruhisa Yamaki, M.D., a clinical fellow at the Kobe University Graduate School of Medicine.

Whilst the immune response to TBM sets up some of the damage, this new research suggests that markers of ongoing neuronal injury are more predictive of disease severity than markers of immune response.

The prospective controlled clinical study tracked biological markers of inflammation in 150 pregnant women who had PCOS and 150 pregnant women of about the same age and body mass index.

«While more research is needed, this study shows that patients in the study had markers of poor prognosis for their melanoma.

And that's apparently improved life for lowlier baboons; they don't have the classic markers of chronic stress — such as elevated levels of stress hormones — found in their peers in other troops.

«Even though their exams and lab tests didn't show much in the way of a common or clear biological marker or markers of PTLDS, it's clear these patients don't feel well,» says study co-author Kathleen Bechtold, Ph.D., associate professor of physical medicine and rehabilitation at the Johns Hopkins University School of Medicine.

There also was no independent association of MCI and intima media thickness (IMT) or coronary artery calcification (CAC), two other surrogate markers of cardiovascular risk.

For the last few years, the sun has been in a relatively quiet phase: there have been few sunspots, which are the markers of a powerful sun.

Using these data, researchers identified four new markers of primary sclerosing cholangitis risk on the human genome, bringing the total number of known predisposing locations to 20.

While we still do not know just how Alzheimer's progresses or what role the fibrils play, they are always found in Alzheimer's - ridden brains and are considered diagnostic markers of the disease.

«We found no truly objective markers of PTLDS on any of these clinically available tests.»

After adjustment for relevant covariates and markers of inflammation, findings persisted in those with RA and not in the controls.

«This study opens avenues for the potential use of proteins that control vesicles and regulate autophagy as novel markers of patient survival,» says Soengas.

Additional risk was associated with being Indigenous and with markers of social disadvantage such as low socioeconomic status.

Their work elucidates a dynamic, two - step mechanism in females whereby B cells lacking the markers of X chromosome inactivation regain these modifications during B cell activation, in a process involving the transcription factor YY1.

In mice, this form of lipodystrophy was also characterized by «whitening» of brown fat cells, a loss of white fat, and signs of metabolic syndrome, including insulin resistance, fat tissue inflammation, dyslipidemia (elevated cholesterol and fat), increased resting energy use, and increased markers of cardiovascular disease.

In a 2011 report, a team led by Todd Atwood of the state Game and Fish Department compared the genetic markers of «mainland» bears living in the forested central part of Arizona with the bears in the mountains near the Mexican border.

One of their goals at the conference was to pinpoint specific markers of these expressions, and then use them to identify the emergence of humans within the paleoanthropological record.

They might also diagnose health conditions by identifying proton - scale differences in molecular mass that are markers of disease.

Mills identified ERP markers of brain plasticity in Williams syndrome in children and adults of varying ages and developmental stages.

The researchers looked at mitochondrial genomes, which are maternally inherited, in a search for markers of Phoenician ancestry.

In a further analysis in which the authors studied the change in BMI and cardiometabolic risk markers of 1,488 young adults over 6 years, the authors found that the cardiometabolic risk profile of an individual was highly responsive to weight change over time.

One study of e-cigarettes was conducted to resemble a smoky bar: the researchers found that markers of nicotine in nonsmokers who sat nearby was similar for both cigarette smoke and e-cigarette aerosol exposure.

At a 0.2 - millimolar sucralose dose similar to the concentration found in the blood of people with high consumption of low - calorie sweeteners — equal to four cans of diet soda per day — the researchers said they observed increased expression of genes that are markers of fat production and inflammation.

But examining blood samples in humans is routine, and Szyf has gone searching there for markers of epigenetic methylation.

«The results of TOPCAT will help inform clinicians as they make treatment decisions for this understudied population,» Added Desai, «If clinicians choose to use this therapy, they must be vigilant about monitoring for serum markers of kidney and electrolyte disorders which can be exacerbated by spironolactone.»

Published in the peer - reviewed journal Systems Biology in Reproductive Medicine, the study, «Sperm RNA elements as markers of health,» from the lab of Stephen A. Krawetz, Ph.D., the Charlotte B. Failing Professor of Fetal Therapy and Diagnosis in the Wayne State Department of Obstetrics and Gynecology and Center for Molecular Medicine and Genetics, indicates that RNA found in male sperm not only shows promise as a determinant in successful live birth, it may also tell us more about the health of a child as it matures.

A regular moderate workout regimen and healthy diet can improve general appearance markers of good health such as muscle tone, healthy skin, hair and nails, while minimizing age or lifestyle - related reductions in health.

They specifically studied the length of telomeres (repeated DNA sequences) on the ends of chromosomes in leukocytes (white blood cells); the protective caps are believed to be markers of biological aging, because they shrink over time.

To look for potential blood - based markers of delirium, a team led by senior investigators Towia Libermann, PhD and Edward Marcantonio, MD, SM, both of BIDMC, screened plasma from adults without dementia aged 70 and older undergoing major non-cardiac surgery using data from the Successful Aging after Elective Surgery Study.

Zheng's team found that relapse patients had significantly elevated levels of PD - 1hiTIM - 3 + cells, which are markers of T cell exhaustion.

Attempts to analyse fetal DNA in the mother's blood for markers of the male - only Y chromosome can give inaccurate results if not enough DNA is available.

Red represents hydroxyl radicals, markers of flame.

«Across the entire project, the degree to which a culture promotes focus on other people rather than the self, including greater awareness of others, was positively associated with all of the markers of emotional complexity,» said Grossmann.

Bipedalism, one of the basic markers of humans, apparently developed long before other traits, such as stone - tool making.

Markers of inflammation in the blood might correlate with clinical signs of hyperalgesia or declining pain thresholds on sensory tests.

Now the researchers set out to identify markers of HD in non-neural tissues that could be used to track the progression of the disease and its response to P110 or other candidate drugs.

In a study published online June 21 in the Annals of Clinical and Translational Neurology, the researchers show that the consumption of extra-virgin olive oil protects memory and learning ability and reduces the formation of amyloid - beta plaques and neurofibrillary tangles in the brain — classic markers of Alzheimer's disease.

Using data from a randomized trial of 206 men treated with either radiation or, radiation and six months of hormonal therapy, researchers compared early markers of prostate cancer death to identify men at risk of dying early.

For some strains of bird flu virus, notably the worrisome H5N1 variant, the genetic changes that could make human - to - human transmission a possibility and spark a pandemic are the markers of intense interest to those who track flu as a threat to human health.

Treated mice had notably improved balance, compared with their untreated counterparts, showing far less head tossing or running in circles, both markers of instability or disorientation.

They then had brain scans to look for markers of brain damage that can be a precursor to dementia.

DNA methylation — the addition of methyl groups to individual bases — is just one of many epigenetic markers of DNA and its associated proteins.

Investigators studied liver tissue from patients with steatohepatitis, who were heavy alcohol drinkers, and from ethanol - fed mice to identify biochemical markers of cellular senescence.

The neural bases of numerosity processing have been investigated in structural and functional neuroimaging studies of adults and children, and neural markers of its impairment in dyscalculia have been identified.

Before the spread of neuroimaging techniques in the late 1990s, there were few objective markers of mental events.

After getting weekly injections for 5 weeks, the mice did not have elevated levels of liver enzymes that signal toxicity, and there was no increase in certain markers of inflammation, or in antibodies that indicate an immune response.

In that study, the UChicago researchers matched genetic markers of the «input» and «output» neurons of the mammalian neocortex with genes expressed in several bird DVR nuclei.

The number of people entering city shelters has increased under de Blasio, and when they enter the system, people are staying longer, striking markers of a crisis that has forced its way to the top of the mayor's agenda.

These are the markers of a civilised society, but they are under relentless attack from corporations and wealthy elites.