Sentences with phrase «markers of disease progression»

The advanced glycation end products and lipid peroxidation products are ubiquitous to diabetes and Alzheimer's disease and serve as markers of disease progression in both disorders.

There are currently no disease - modifying treatments that have been shown to slow the progression or delay the onset of HD in humans; however, several compounds have demonstrated promise in animal models of HD.1 Robust and sensitive markers of disease progression are required to assess their efficacy in humans.

Such models can allow integrating different kinds of patient data: from the level of medical substances in the blood and how these affect the patient's physiology, markers of the disease progression to symptoms and survival.

Physicians will monitor the patient's levels of prostate specific antigen (PSA), a marker of disease progression.

«Tau aggregates to form the hall - mark tangles of Alzheimer's disease and serves as the best marker of disease progression.

Not exact matches

Now the researchers set out to identify markers of HD in non-neural tissues that could be used to track the progression of the disease and its response to P110 or other candidate drugs.

Researchers at Stanford University School of Medicine have identified several new biological markers to measure the progression of the inherited neurodegenerative disorder Huntington's disease (HD).

Smith says her group is investigating whether PET imaging of serotonin could be a marker to detect progression of disease, whether alone or in conjunction with scans that detect the clumping protein known as amyloid that accumulates in the brains of those with Alzheimer's disease.

Second, fibrosis is a marker of progression to chronic kidney disease, suggesting that the paracrine effects could act as preventative therapy for other serious ailments.

The researchers note that CD8 + T cells could potentially be used as markers for the progression of fatty liver disease, which is expected to become the leading indication for liver transplantation within the next one or two decades.

Plasma levels of sNKG2D - L, and verexpression of ADAM10, correlate with disease progression and are prognostic marker in some hematologic malignancies, including Hodgkin lymphomas (HL).

Notably, NfL is not specific for HD and has also been proposed as a marker to track the progression of other neurodegenerative diseases, including Alzheimer's and ALS.

The Parkinson's Progression Markers Initiative (PPMI) is a landmark observational clinical study to comprehensively evaluate cohorts of significant interest using advanced imaging, biologic sampling and clinical and behavioral assessments to identify biomarkers of Parkinson's disease pProgression Markers Initiative (PPMI) is a landmark observational clinical study to comprehensively evaluate cohorts of significant interest using advanced imaging, biologic sampling and clinical and behavioral assessments to identify biomarkers of Parkinson's disease progressionprogression.

Those researchers concluded that preventative treatment of normal TSH range patients with Hashimoto's disease reduced the various markers of autoimmune thyroiditis, and speculated that such treatment might even be able to stop the progression of Hashimoto's disease, or perhaps even prevent the development of the hypothyroidism.