Just as high blood pressure, high cholesterol or sleep apnoea are
markers of disease risk, so is obesity.
Not exact matches
Household income has been shown to interact with child growth in Brazil.21 A US study
of diarrhoeal
disease found no interaction between breast feeding and household income.8 Household income, like social class, may not be a good
marker of transmission
risk.
Individuals were classified as high
risk for Alzheimer's if a DNA test identified the presence
of a genetic
marker — having one or both
of the apolipoprotein E-epsilon 4 allele (APOE - e4 allele) on chromosome 19 — which increases the
risk of developing the
disease.
In other words, she says, personality constructs emerging from the basic biology
of the brain can be yet another
marker that the individual is at
risk for TILT, and easier to sensitize to the
disease.
Although tau imaging is still in its earliest stages, Ryan hopes that such imaging will accelerate drug development and that finding a blood - based biomarker for Alzheimer's to reveal
risk (much like cholesterol serves as a
marker for cardiovascular
risk) will change the field dramatically in terms
of how doctors can diagnose the
disease.
«Our analysis suggests that migraine should be considered an important
risk marker for cardiovascular
disease, particularly in women,» concludes Prof. Kurth, adding that: «The
risk of developing cardiovascular events was shown to be 50 % higher in women with a diagnosis
of migraine.
As Maurizio Battino, researcher at UNIVPM and Director
of the study, said: «This is the first time a study has been published that supports the protective role
of the bioactive compounds in strawberries in tackling recognised
markers and
risk factors for cardiovascular
diseases.»
All had abnormalities
of TP53 or ATM — two mutations associated with high -
risk disease — and two patients had increasing BTK C481S clones, also a high -
risk marker.
Indeed, low birth weight, a
marker of impaired fetal development, is associated with increased everyday levels
of inflammatory
markers as well as greater
risks of heart
disease, diabetes, depression and schizophrenia in adults.
With additional research and knowledge, she said, it may also be possible one day to use these epigenetic changes as
markers, which can tell that a child is at
risk of obesity and other
diseases.
The study also found distinct blood pressure patterns from ages 18 to 55 that reveal people at high
risk for calcification
of coronary arteries — a
marker for heart
disease — by middle age.
«Our study suggests that short height in children is a possible
marker of stroke
risk and suggests these children should pay extra attention to changing or treating modifiable
risk factors for stroke throughout life to reduce the chances
of having this
disease,» said senior study author Jennifer L. Baker, Ph.D., associate professor in the Center for Clinical Research and Prevention at Bispebjerg and Frederiksberg Hospital and Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty
of Health and Medical Sciences, at the University
of Copenhagen, in Denmark.
An antibody used to treat the skin
disease psoriasis is also effective at reducing aortic inflammation, a key
marker of future
risk of major cardiovascular events.
«Women with migraines have higher
risk of cardiovascular
disease, mortality: Migraine should be considered an important
risk marker for cardiovascular
disease, say experts.»
While attending a conference, Orszag learned from biologist Craig Venter that he could get screened for a genetic
marker that can raise the
risk of heart
disease when lots
of caffeine is consumed.
Two proteins, which have not previously been linked to pre-eclampsia
risk, were shown to be at least as good a predictor
of disease risk as the current best
marker, placental growth factor,.
«We've got a
marker for biological aging — telomere length — so we're studying whether we can relate it to the increased
risk of getting some
of these age - associated
diseases.
Doctors measure levels
of triglycerides as a
marker of heart
disease risk, though whether these fats play a role in causing plaque to build up in arteries historically has been a matter
of debate.
«Our ability to pinpoint CRP levels as being significantly elevated before and after postoperative delirium onset establishes CRP as a
risk marker, as well as a
disease marker, for delirium,» said Sarinnapha Vasunilashorn, co-first author
of the study, along with Simon Dillon, also
of BIDMC.
Compared to the control group, kidney stone formers maintained higher levels
of the blood
marker cystatin C and higher levels
of urine protein — both
of which are connected with higher
risk of chronic kidney
disease.
These recommendations are based largely on a body
of research that links higher sodium intakes to certain «surrogate
markers» such as high blood pressure, an established
risk factor for heart
disease.
Instead they measure surrogate
markers — outcomes that are associated with a
risk of disease — but not a bad outcome itself.
«While we don't know which comes first — depression or cardiovascular
disease — the consensus is that depression is a
risk marker for cardiovascular
disease, meaning if you have cardiovascular
disease, there is a higher likelihood that you could also have depression, when compared with the
risk in the general population,» said Victor Okunrintemi, M.D., M.P.H., a research fellow at Baptist Health South Florida in Coral Gables, Florida, and lead author
of a pair
of studies that looked into different aspects
of depression and cardiovascular
disease.
The study was carried out by a team
of researchers from two global scientific consortia, ENIGMA and CHARGE, which began to pool their brain imaging and genetic datasets back in 2009 to look for genetic
markers that affect one's
risk of developing brain
diseases.
Our diets can also change our metabolism as well as the levels
of circulating factors (hormones, lipids, etc.) which may be
markers for
disease risk.
At City
of Hope Cancer Center in Duarte, California, Rick Kittles is exploring the link between ancestry - informative genetic
markers and
disease risk and outcomes, with a special emphasis on prostate cancer.
REVEAL IV is the first translational genetics study to focus upon the situation where mild early symptoms
of a
disease (phenotype) and known genetic
risk marker (genotype) information can be used together to produce more imminent
risk projections.
The results suggest that elevated plasma levels
of inflammatory biomarkers, including complement proteins, associate with polygenic
risk scores in AD, further strengthening the link between genetic and biomarker
disease predictors and indicating a potential role for these
markers in
disease prediction and patient stratification in AD.
Gene
Markers Located for Hereditary Prostate Cancer Researchers at the Johns Hopkins Brady Urological Institute, Wake Forest University and the Karolinska Institute in Sweden identified an array of gene markers for hereditary prostate cancer that, along with family history for the disease, appear to raise risk to more than nine times that of men without such m
Markers Located for Hereditary Prostate Cancer Researchers at the Johns Hopkins Brady Urological Institute, Wake Forest University and the Karolinska Institute in Sweden identified an array
of gene
markers for hereditary prostate cancer that, along with family history for the disease, appear to raise risk to more than nine times that of men without such m
markers for hereditary prostate cancer that, along with family history for the
disease, appear to raise
risk to more than nine times that
of men without such
markersmarkers.
Such work has become increasingly important given the expansion
of genome - wide association studies identifying genetic
risk factors for common
diseases and corresponding efforts to commercialize genetic testing using these
markers.
CLA may raise levels
of the inflammatory
marker C - reactive protein, which could up your
risk of heart
disease.
Even further, studies on high - fat diets show that increased consumption
of saturated fat has beneficial impacts on cardiovascular
disease risk markers, including decreasing the level
of triglycerides, fasting glucose, blood pressure, as well as increasing HDL cholesterol blood levels.
Doctors have speculated that folic acid may improve heart health, because people with B - vitamin deficiencies often have high blood levels
of the amino acid homocysteine, a
marker of inflammation that has been linked to an increased
risk of heart
disease.
Next Page: Treatment options [pagebreak] Implications for treatment Though the exact role
of inflammatory
markers is yet to be determined, if your CRP test uncovers high levels
of CRP (defined by the American Heart Association as over 3 mg / L), it is probably a sign that you should address your
risk for cardiovascular
disease, even if you have normal cholesterol.
If the FDA adopts the panel's recommendation — the agency isn't required to do so, but typically does in such cases — it would mark the first time that a statin was approved for heart -
disease - free people with healthy cholesterol levels but other
risk factors, including high levels
of C - reactive protein (CRP), a
marker of inflammation.
«Finding this association with a strong
marker of Alzheimer's
disease risk reinforces the idea that being underweight as you get older may not be a good thing when it comes to your brain health,» he added.
Interestingly, this ratio is also correlated with less
risk of certain
diseases and higher health
markers.
In another study
of overweight adults, eating fermented full - fat dairy products — ie, cheese and yogurt — resulted in a greater reduction in inflammatory
markers known to increase heart
disease risk compared to low - fat versions
of these dairy products (26).
Surprisingly, the researchers did not find increased levels
of Alzheimer's
markers when they looked specifically at people with obstructive sleep apnea, a breathing disorder that's a major disruptor
of sleep and a
risk factor for several other chronic
diseases.
Everyone knows that going to the gym on a regular basis and putting yourself under relatively heavy mechanical stress repeatedly can improve a variety
of health
markers and decrease the
risk of developing lots
of different conditions, from diabetes, heart to neurological
diseases.
It can also work in conjunction with chromium to reduce LDL levels and increase HDL since inverse levels
of each are
markers for increased
risk of heart
disease.
The researchers found that all four were effective in improving various
markers of cardiovascular
disease risk in people with diabetes, «and could have a wider role in the management
of diabetes.»
Considering that the hs - CRP inflammation
marker is associated with
risk of diseases such as cancer, dementia, cardiovascular
disease, and many other chronic
diseases, «if you have to take one test, this might be the one.»
It has been seen to improve diabetes and high cholesterol in a number
of clinical studies, as well as improve
risk markers of cardiovascular
disease and even constipation.
The study suggests that low testosterone may be a predictive
marker for those at high
risk of cardiovascular
disease.
These CR - induced changes suggest a shift toward a healthy phenotype, given the established role
of these pro-inflammatory molecules as
risk markers in the development
of metabolic syndrome and age - related chronic
diseases, in particular CVD, T2D and cancer (1).
(2) Adiponectin is a
marker of cardiovascular
disease and type 2 diabetes
risk.
A recent trial — The effects
of intermittent or continuous energy restriction on weight loss and metabolic
disease risk markers: a randomized trial in young overweight women — compares CRaP to IF.
In one study in 2010, researchers studied the effects
of consumption
of a sheep's milk pecorino cheese on atherosclerotic biomarkers (indicating
risk for heart
disease), and found that the dairy fat in this cheese improved the subjects
markers!
«Most
risk markers for cardiovascular
disease have a pro-inflammatory component, which stimulates the release
of a number
of active molecules,» researchers in one study argue.