Sentences with phrase «market decreasing the level»

The trial may become a dangerous precedent in the cryptocurrency market decreasing the level of confidentiality of the cryptocurrency world.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Cryptanalysts believe that Tron's decreasing price levels may be a direct symptom of the on - going struggles in both the Bitcoin and Ethereum market.

At a market level, prices are projected to decrease most in already high - cost markets, like New York, Philadelphia, Washington D.C., San Francisco and Los Angeles.

Evidence clearly shows that for many employee owners their share price decreased, but not at the levels we saw in the public stock market.

CDS levels have decreased for emerging - market countries relative to where they were 15 years ago.

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

Storage time may also decrease * the nutrition levels of fruits and vegetables, from harvest to shipping and shelving in stores and markets.

Super-DMZ Rx 5.0 tackles this problem head - on by employing one of the most effective natural myostatin inhibitors on the market, which has been clinically proven to not only increase follistatin production, but decrease myostatin levels as well.

The strong market and demand for Honda vehicles has led to record breaking sales which have decreased Honda inventory levels here at our San Diego Honda dealership.

This would naturally imply, as many market experts often maintain, that the absolute best investment strategy is simply to place all of one's investment funds into an index fund, which would increase or decrease according to the overall level of corporate profitability or losses.

On the other hand, if the market believes that the FOMC has set the fed funds rate too high, the opposite happens — long - term interest rates decrease because the market believes future levels of inflation will decrease.

There is No Guarantee that the Index Level Will Decrease or Increase by 1.00 Point For Every 0.01 % Change in the Level of the Underlying U.S. Treasury Note or Bond Yield or U.S. Treasury Yield Curve: Reasons why this might occur include: market prices for underlying U.S. Treasury note or bond futures contracts may not capture precisely the underlying changes in the U.S. Treasury note or bond yield or the U.S. Treasury Yield Curve, as the case may be; the index calculation methodology uses approximation; and the underlying U.S. Treasury note or bond weighting is rebalanced monthly.

The earliest ARMs didn't offer any discount on the initial rate — no «teasers» here — but instead the opportunity that your mortgage rate and monthly payment would decrease as market interest rates returned more toward normal levels.

If market interest rates decrease in the future, and cause the variable rate to adjust downward to a level lower than the business» original fixed rate, the business would be paying less interest.

If market interest rates decrease to a level lower than the fixed rate, the business would be paying more interest.

In years when the market declines, freeze your withdrawal at the previous year's level, or decrease it to your bare essentials.

Unfortunately, the market has continued to trend way downward, and the amount of equity in our house has decreased tremendously to the point that we are nowhere near the level where we have 20 % equity in our home.

As markets continue to stabilize and inventory levels return to normal, prices are expected to decrease slightly over the rest of this year.

96 of the nation's top 100 markets (by population) had drops in traffic congestion levels in the first half of 2008 compared to 2007, with a 3 % nationwide average decrease in travel times during peak hours.

There are many different kinds of term life insurance policies, such as return of premium, guaranteed level, and decreasing term life insurance, available on the market.

Cryptanalysts believe that Tron's decreasing price levels may be a direct symptom of the on - going struggles in both the Bitcoin and Ethereum market.

Percent price decreased is an insightful gauge of demand levels in the residential housing market.

The company says that if economic models for the multifamily market are correct, Fannie Mae and Freddie Mac's share of the market will decrease from 44 percent in 2012 «to the 30 percent level or below» for 2013.

For 2007 the Board approved a budgeted membership of 1,230,000, a decrease of 10 percent from the current level of 1,366,000, which reflects the slowdown in markets across the country.