Not exact matches
Fueled
by low prices, and an improving job
market, consumption
of gasoline in the U.S. rose
by 2.6 per cent last year to 9.2 million barrels a day, the highest
level since 2007, the
government said.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount
of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and
government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability
of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven
by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings;
market share and price erosion caused
by the introduction
of generic versions
of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other
government action that could have the effect
of lowering prices or reducing the number
of insured patients; the possibility
of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the
levels of inventory held
by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits
of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages
of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development
of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other
market conditions; fluctuations in the foreign exchange rate
of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
International investments, particularly investments in emerging
markets, may carry risks associated with potentially less stable economies or
governments (such as the risk
of seizure
by a foreign
government, the imposition
of currency or other restrictions, or high
levels of inflation or deflation), and may be or become illiquid.
Dr. Richard Swart, who heads the Crowdfunding Research Program at the University
of California, Berkeley, has cited several experts who project that the size
of the securities crowdfunding
market will range from «$ 3.98 billion (Nest, Neiss, Stralser & Fleming 2013) to as much as $ 300 billion over the coming years depending on the
level of enabling regulation adopted
by governments.»
While many aspects
of the new legal
market involve coordination between
levels of government across the country, regulation and licensing
of producers to supply the recreational
market is a federal responsibility administered
by Health Canada.
However, the public can not contribute to the marginal public - sector investment, since the
level of public investment is determined
by the
government and not
markets.
During 2014 - 16, he has been an active member
of the High
Level Committee set up
by the
government (NDA - II) to restructure the food management system in the country (known as Shanta Kumar Panel); member
of the Task Force set up
by the Prime Minister under NITI on Agriculture Sector Reforms; and also Chairing a Committee for Agri -
Marketing Reforms in the country.
On Tuesday, the
governments of California and six other western states as well as four Canadian provinces proposed a new plan to cut greenhouse gas emissions
by 15 percent below 2005
levels by 2020 using a similar cap - and - trade
market — and would expand such regulations to encompass not just CO2 from power plants but also cars and trucks as well as other greenhouse gases, such as potent methane.
In the K - 12 education
market, where countries the world over publicly finance and manage the great majority
of their schools, the institutions and policies established
by various
levels of government must create incentives for school personnel to use their resources in ways that maximize performance.
The letter laid out a plan «to remold the entire American system» into a centralized one run
by «a system
of labor -
market boards at the local, state and federal
levels» where curriculum and «job matching» will be handled
by government functionaries.
Pursuing income with an all - weather bond portfolioDiverse opportunities: The fund invests across all sectors
of the U.S. bond
market, including mortgage - backed, corporate, and
government bonds.A flexible strategy: The portfolio managers pursue an attractive
level of income, adjusting the portfolio to favor attractive sectors as interest rates and
market conditions change.Leading research: The managers, supported
by Putnam's fixed - income research division, analyze a range
of bonds to build a competitive portfolio.
The investment objective
of the Scheme is to provide reasonable returns and high
level of liquidity
by investing in debt instruments such as bonds, debentures and
Government securities; and money
market instruments such as treasury bills, commercial papers, certificates
of deposit, including repos in permitted securities
of different maturities, so as to spread the risk across different kinds
of issuers in the debt
markets.
International investments, particularly investments in emerging
markets, may carry risks associated with potentially less stable economies or
governments (such as the risk
of seizure
by a foreign
government, the imposition
of currency or other restrictions, or high
levels of inflation or deflation), and may be or become illiquid.
In fact different participants may have radically different motives including the fact that some may be sincere, some appear to be motivated
by protecting free
markets without
government intervention, and many appear to believe that no restriction on fossil fuel use can be justified without very high
levels of proof
of harms.
On Tuesday, the
governments of California and six other western states as well as four Canadian provinces proposed a new plan to cut greenhouse gas emissions
by 15 percent below 2005
levels by 2020 using a similar cap - and - trade
market — and would expand such regulations to encompass not just CO2 from power plants but also cars and trucks as well as other greenhouse gases, such as potent methane.
A «hot»
market creates challenges for our industry, and that's compounded
by the compliance required for the growing multiplicity
of laws and regulations from various
levels of government.
«After years
of trying to keep up with rising rents, it's time we take a more holistic look at how
government at every
level, working with the private
market and others, can ease the pressure being felt
by too many unassisted renters.
Since
government mortgage applications for purchase were less effected
by the boom and bust cycle in the housing
market, restoring the
level of total mortgage applications will require continued recovery on the conventional side.