Data delivered includes the full data set for each genome within the Sample Group as well as results from paired analysis between the tumor and
the matched normal genome samples.
Not exact matches
First of all, only the metastatic sample was whole -
genome sequenced — the primary tumor and
matched normal were not.
By conducting an RNA - sequencing experiment of 103
matched tumour and
normal colon mucosa samples from Danish CRC patients, 90 of which were germline - genotyped, researchers from the collaborative European project SYSCOL show that both inherited and acquired mutations in non-coding regions of the
genome also contribute to cancer development and progression (Linda Koch, Nature Reviews Genetics).
Zhang et al performed whole -
genome sequencing on tumor samples and
matched normals from 12 children with ETP - ALL.
By sequencing the complete
genomes of primary tumor, relapsed tumor, and
matched normal (skin) samples from 8 AML patients, our group was able to study clonal evolution of AML tumors at the genetic level.
This public
genome repository comprises
genome results from both our Standard Sequencing Service (69 standard, non-diseased samples) and the Cancer Sequencing Service (two
matched tumor and
normal sample pairs).
To help the patient, and also make some advances in tech development, Jones and his colleagues did whole -
genome and RNA - Seq of the tumor samples and
matched normals.
As part of the Cancer
Genome Atlas Project (TCGA), we've been applying both targeted (capture - based) and whole - genome sequencing approaches to tumor samples and matched normal con
Genome Atlas Project (TCGA), we've been applying both targeted (capture - based) and whole -
genome sequencing approaches to tumor samples and matched normal con
genome sequencing approaches to tumor samples and
matched normal controls.
359/10: 30 The importance of assaying the
matched normal when sequencing cancer
genomes.