Sentences with phrase «maternal treatment»

The effects of chronic prenatal hypoxia on the fetal and adult offspring cardiovascular system are prevented by maternal treatment with vitamin C during pregnancy.

Therefore, the primary novelty of the discoveries reported here is that programming by prenatal chronic hypoxia of cardiac and vascular dysfunction in adulthood follows the induction of oxidative stress in the fetal heart and vasculature, and that cardiac and endothelial dysfunction in adulthood can both be prevented by maternal treatment with antioxidants during pregnancy.

It is interesting that the balance of redox modulation of vascular tone, imposed by the O2 • −: NO ratio, may be tipped in either direction to promote disequilibrium, as maternal treatment with vitamin C in normoxic pregnancy also promoted endothelial dysfunction.

[10] Dennis, C.L., and Leinic, C.L. «Postpartum depression help ‐ seeking barriers and maternal treatment preferences: A qualitative systematic review.»

The implications of these data are that maternal treatment with antioxidants may provide possible therapy against the programming effects on vascular dysfunction in pregnancy complicated by fetal hypoxia, such as during placental insufficiency, preeclampsia, gestational diabetes or high altitude pregnancy.

Further data reported in this study show that maternal treatment with vitamin C increased birth weight in both normoxic and hypoxia pregnancy.

The mechanism mediating this may be secondary to the increased NO bioavailbility enhancing placental perfusion, as we have previously also reported that maternal treatment with antioxidants can enhance umbilical blood flow and fetal growth via NO - dependent mechanisms [59], [60].

The study revealed double the risk of autism spectrum disorders linked to maternal treatment with SSRI antidepressants in the year before delivery with treatment in the first trimester associated with the strongest effect.

We previously reported the demographic and clinical characteristics of the mother - child pairs before the commencement of maternal treatment.14 Our focus herein is on the symptomatic and behavioral functioning of the children assessed 3 months after the initiation of treatment of maternal depression by a team of evaluators not involved in maternal treatment and unaware of maternal outcomes.