Read on for our client highlights in September: Product injury firm Hissey Kientz introduced a new service page: a microsite for information on birth defects associated with
maternal use of the antidepressant Paxil, side effects of Paxil, news items about Paxil... more»
Not exact matches
«We have demonstrated for the first time in an animal model that
maternal use of a class
of antidepressants called selective serotonin reuptake inhibitors, or SSRIs, resulted in increased fat accumulation and inflammation in the liver
of the adult offspring, raising new concerns about the long - term metabolic complications in children born to women who take SSRI
antidepressants during pregnancy,» says PhD student Nicole De Long, who presented this research on June 22nd at the joint meeting
of the International Society
of Endocrinology and The Endocrine Society.
«Obesity and Type 2 diabetes in children is on the rise and there is the argument that it is related to lifestyle and availability
of high calorie foods and reduced physical activity, but our study has found that
maternal antidepressant use may also be a contributing factor to the obesity and diabetes epidemic,» said the study's senior investigator Alison Holloway, associate professor
of obstetrics and gynecology at McMaster University.
«While it is known that these drugs can increase the risk
of obesity in adults, it is unknown whether a woman's
antidepressant use during pregnancy increases the risk
of metabolic disturbances in her children,» Holloway says, adding the goal
of their project was to determine whether
maternal exposure to a commonly
used antidepressant is related to the development
of fatty liver, an outcome commonly seen with obesity, in the offspring.
The
use of a single
antidepressant in an open - trial design without a placebo control did not allow us to rule out that
maternal remission was due to nonspecific treatment effects or whether the relation
of maternal remission to children's outcomes may have been different if another medication or psychotherapy had been
used.