Not exact matches
Once they were able to isolate skeletal muscle
cells using the newly identified surface
markers, the research team
matured those
cells in the lab to create dystrophin - producing muscle fibers.
They removed spermatogonia labeled with a fluorescent
marker from a
mature male trout and injected the
cells into the abdomens of newly hatched male and female trout fry.
The scientists also found that a protein known as CD29 acts as a
cell - surface
marker for precursor fat
cells that can generate
mature cells with high energy potential, as shown by their UCP1 expression.
To verify that the individual
cells they picked were pure, the researchers cultured them for several days to determine, using
cell markers, whether they formed
mature HSCs.
After 15 days, a subset of
cells expressed regulators of RGC differentiation (Atoh7, Brn3b, and Islet1), while a smaller subset co-expressed Brn3b and the
mature RGC
marker Thy1, thus confirming a RGC identity.
These studies led to identification of a
cell surface protein that is a useful
marker of positive selection and is a likely regulator of
mature lymphocyte and APC function.
We have previously reported that our 26 - d protocol closely recapitulates key stages of biliary development, starting with the differentiation of hPSCs into endoderm and subsequently into foregut progenitor (FP)
cells, followed by the generation of hepatoblasts (HBs), cholangiocyte progenitors (CPs) expressing early biliary
markers and
mature CLCs displaying cholangiocyte functionality.
We found that differentiated iPS - RPE
cells were morphologically similar to, and expressed numerous
markers of developing and
mature RPE
cells.