Sentences with phrase «mature cell reprogrammed»

iPS cells are mature cells reprogrammed to behave like those from an early embryo.

And at Japan's RIKEN Center for Developmental Biology, one pioneering group is taking induced pluripotent stem cells (iPS), mature cells reprogrammed to return to a state of pure potential, and turning them into RPE cells.

Not exact matches

To avoid the controversy surrounding these cells, scientists around the world have explored reprogramming mature cells to make them just as potent, with the hope being that such induced pluripotent stem (iPS) cells might one day help replace diseased or damaged tissue.

In a process called cellular reprogramming, researchers at Icahn School of Medicine at Mount Sinai have taken mature blood cells from patients with myelodysplastic syndrome (MDS) and reprogrammed them back into iPSCs to study the genetic origins of this rare blood cancer.

In addition, scientists want to learn more about how an oocyte can reprogram a mature cell back into an ES cell.

The award was given for their work showing that mature cells can be reprogrammed into pluripotent stem cells.

This is all it takes for a so - called precursor fat cell to have its «epigenetic recipe» on how to correctly develop into a mature fat cell, reprogrammed.

He was awarded the 2012 Nobel Prize along with Sir John Gurdon «for the discovery that mature cells can be reprogrammed to become pluripotent.»

«We believe that in obese individuals the muscle stem cells have been reprogrammed, and that this may partly explain why muscle cells in obese people have decreased insulin sensitivity and lower metabolism after they have matured,» says Cajsa Davegårdh.

TOKYO — An investigating committee has concluded that falsification and fabrication mar two recent Nature papers reporting a new, simple way to reprogram mature cells into stem cells.

Dr Peter Rugg - Gunn, group leader in the Babraham Institute's Epigenetics research programme and a senior co-author on the paper, explains: «One of the exciting aspects of this study is that we were able to capture naïve stem cells at a very early stage of their reprogramming — these early cells had switched on a subset of naïve - specific genes, but they had not yet fully matured.

The researchers found the identical mixture of sensory interneurons developed when they added the same signaling molecules to induced pluripotent stem cells, which are produced by reprogramming a patient's own mature cells such as skin cells.

«Our earlier work was the first to clearly show in vivo (in a living animal) that mature astrocytes can be reprogrammed to become functional neurons without the need of cell transplantation.

In collaboration with researchers at the University of California, San Francisco (UCSF), Dr. Ding and his team — once again harnessing the power of chemical reprogramming — surmounted previous challenges to generate fully mature, functional liver cells.

He is the principal investigator of an NCI - funded, multi-million-dollar Specialized Program of Research Excellence (SPORE) in ovarian cancer, and he is the principal investigator of a multi-million-dollar grant from the New York State Stem Cell Science program (NYSTEM) to pioneer a novel strategy of reprogramming human mature T cells and hematopoietic stem cells for generating sustained attack against ovarian cancer in patients.

Surprisingly, by introducing only a few genes, he could reprogram mature cells to become pluripotent stem cells, ie immature cells that are able to develop into all types of cells in the body.

This study for the first time demonstrates that ER71 / ETV2 alone can directly reprogram human postnatal cells to functional, mature ECs after an intervening transgene - free period.

A director of the Max Planck Institute for Molecular Biomedicine in Münster, Germany, Schöler investigates how mature body cells can be reprogrammed into pluripotent stem cells.

The choice of the somatic cell for reprogramming, the reprogramming technology chosen, and the differentiation techniques utilised, all work synergistically towards the production of mature iPSCs - derived chondrocytes which are comparable to patient - derived chondrocytes, in line with Good Manufacturing Practice guidelines for an «off - the - shelf» stem cell product.

Determining how an embryonic stem cell differentiates into mature cells might eventually allow development of methods to reprogram an adult cell.