Sentences with phrase «mature cells expressing»

Actively regenerating tissues expressing a gene have mRNAs with shorter tails, while mature cells expressing that same gene have mRNAs with longer tails,» says Vairavan Lakshmanan, who is one of the lead authors of the paper that details these findings.

Not exact matches

«Other miRNAs were being expressed in high levels in the more mature cells, but let - 7 had increased 1000-fold.

Although myeloma is, like leukemias and lymphomas, a cancer involving white blood cells known as lymphocytes, myeloma cells don't traditionally express CD19 on their surface because they arise from the most mature type of lymphocytes — plasma cells.

«Promoter» areas, locations where genes begin to be expressed, must be paired precisely with «enhancer» clusters, where cells mature to a targeted function.

The researchers saw that in early stages, two days after the mice were born, developing rod cells expressed genes normally seen in mature short - wavelength cones (which are used in other animals to detect ultraviolet light).

These cells express common and unique extracellular matrix and tendon genes that are more specialized to support the mature scar.

EFTF - expressing pluripotent cells form functional retinal cells and eyes when transplanted to the developing embryo, but can these induced retinal cells also differentiate into all the functional retinal cell classes in a mature normal or damaged retinal environment?

Deciphering the role in cancer of «non-conventional» T cells that recognize lipid antigens presented by CD1 molecules, non-polymorphic MHC - I - related molecules expressed by mature myeloid and B cells.

We also cultured animals in BrdU and used immunocytochemistry to detect mitotically active cells in mature retinas generated from EFTF - expressing cells.

After 15 days, a subset of cells expressed regulators of RGC differentiation (Atoh7, Brn3b, and Islet1), while a smaller subset co-expressed Brn3b and the mature RGC marker Thy1, thus confirming a RGC identity.

These results suggest that EFTF - expressing cells are multipotent, as they differentiate into the seven retinal cell classes of the mature retina.

In the thymus, expression of CD4 and CD8 varies during T cell maturation, such that cells initially do not express CD4 or CD8 (double negative [DN]-RRB- after arriving to the thymus, then express both CD4 and CD8 (double positive [DP]-RRB- after TCR rearrangement, and finally downregulate either CD4 or CD8 to generate mature single - positive cells that exit into the periphery.

Two other more mature brain cell types, astrocytes and microglia, which can migrate in the brain, also express the AXL gene.

BTLA is also expressed by all mature lymphocytes, splenic macrophages, and mature, but not immature bone marrow - derived dendritic cells.

Glial cell line - derived neurotrophic factor (GDNF) was selected based on clear evidence that it increases neuronal sprouting, prevents cell death [20], [21] and has neuroprotective effects in the brain [11], [22]--[24], spinal cord [12] and retina [25]--[30], and because receptors for GDNF are expressed within mature retina [26], [31]--[34].

We have previously reported that our 26 - d protocol closely recapitulates key stages of biliary development, starting with the differentiation of hPSCs into endoderm and subsequently into foregut progenitor (FP) cells, followed by the generation of hepatoblasts (HBs), cholangiocyte progenitors (CPs) expressing early biliary markers and mature CLCs displaying cholangiocyte functionality.

We found that differentiated iPS - RPE cells were morphologically similar to, and expressed numerous markers of developing and mature RPE cells.

Then Hu expressed lincRNA - EPS in maturing red blood cells and grew these cells in the absence of the hormone erythropoietin, which normally prevents the blood cell progenitors from undergoing apoptosis.