Sentences with phrase «mature oligodendrocytes»

In the healthy brain, stem cell - like glial progenitors can divide, migrate to an injured site, and become mature oligodendrocytes after myelin loss, but, unfortunately, the efficiency of remyelination declines with age.

Not only were Miconazole and clobetasol able to stimulate the differentiation of stem cells into mature oligodendrocytes, most importantly, these drugs stimulated the formation of new insulation (myelin) and reversed disease severity in animal models of MS.. While not all adult tissues in our body contain stem cells, this approach may change the way MS is managed.

Here Dr. Reimer and his team asked the question, «what happens to mature oligodendrocytes after a spinal cord injury in adult zebrafish?».

Finally, they demonstrated that zebrafish OPCs differentiate into mature oligodendrocytes when cultured together with human motor neurons, differentiated from induced pluripotent stem cells.

One mature oligodendrocyte can coat about 50 axon segments with myelin.

Not exact matches

But in people with MS, some oligodendrocytes stop making myelin altogether and young oligodendrocytes have trouble maturing.