A biomarker used to
measure cell proliferation found a decrease in the activation of CD4 + T cells in the colon of the monkeys given both ARVs and probiotics while a cytokine test found the «overall functionality» of the CD4 + T cells in the colon of the probiotic arm had improved.
The challenge to
measure cell proliferation in two and three dimensions.
Not exact matches
When those
cells were placed on a standard wound assay (for
measuring properties like
cell migration and
proliferation), they moved unusually fast.
Monitoring immune
cell activity — including phenotyping immune
cell subsets, tracking
cell proliferation, and
measuring cytokine production — can provide insights into the overall status of immune function in patients, particularly those undergoing immunosuppression after transplants, enduring cancer treatment, or suffering from autoimmune disease or other pathologies that affect the immune system.
The degree of lymphocyte
proliferation, regulatory T -
cell generation and cytokine secretion were
measured.
After the incubation,
cell proliferation was
measured by the MTS dye method (Promega).
But this selection method has one drawback: it determines an antibody's ability to activate a desired biological pathway in a
cell by
measuring the resulting
proliferation of that
cell — a slow and only narrowly applicable indicator.
We then
measured the
proliferation of these
cells with increasing concentrations of INCB018424 and calculated the IC50 (Online Supplementary Figure S3B).
In addition to receptor binding, the assays
measure key events along the ER adverse - outcome pathway, such as receptor dimerization, DNA binding, transactivation, gene expression, and
cell proliferation.
To assess the ability of F3 - IgG to inhibit the
proliferation of HER2 - overexpressing breast carcinoma
cells, we
measured the
proliferation of BT474, MCF7 / HER2 and MCF7 breast cancer
cell lines in the presence of trastuzumab, F3 - IgG, or an isotype - matched control antibody.
Unlike normal plasma
cells, the malignant plasma
cells look large and round with a high mitotic index (
measure of the
proliferation of a
cell population) in early stages of cellular differentiation.