Sentences with phrase «measure change in rates»

If there is a 60 year signal here, it would seem like you would want to measure change in rates as peak to peak from 1940 to 2000 versus a (1960 to 1980) vs (1980 to 2000) which would not be representative due to the multi-decadal cycle.

For instance, we can give smokers different concoctions containing cruciferous vegetables and measure changes in their rate of excretion of toxins from cigarette smoke (as opposed to the harmful metabolism of them within the body).

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

2 The percentage change has been calculated using actual exchange rates in use during the comparative prior year period to enhance the visibility of the underlying business trends by excluding the impact of translation arising from foreign currency exchange rate fluctuations, which is considered a non-GAAP financial measure.

Duration is a measure that helps estimate the amount the price of a bond will rise or fall in response to changes in interest rates.

Duration, the most commonly used measure of bond risk, quantifies the effect of changes in interest rates on the price of a bond or bond portfolio.

«Given the necessity for continuous vendor management, it's important for us to invest in a company that has the potential to truly change the way all organizations measure risk and rate cyber security performance.

IMF estimates of annual growth rate of world real GDP (in red, right scale) and year - over-year percent change in commodity prices as measured by the quarterly average CRB / BLS raw industrials price index (in green, left scale).

Duration represents a measure of the sensitivity of the price (the value of principal) of a fixed - income investment to a change in interest rates.

If so, apparent neutral real interest rates will decline even if there is no change in properly measured rates.

«China has paved the way for a further weakening of its currency by announcing changes in how it measures the value of the renminbi, raising investors» alarm at the prospect a new currency war just as the US prepares to raise interest rates» (FT, 12/12/15).

S&P Indices and Experian today released September data for the S&P / Experian Consumer Credit Default Indices, which measure changes in consumer credit defaults; and the data showed increases in default rates across most consumer credit lines.

Measured across all loan products, and taking into account changes in customer risk margins, however, it seems that interest rates paid on average by small businesses have increased by a little less than the rise in interest rates directly due to the tightening of monetary policy.

Duration is a measure of the sensitivity of the price (the value of principal) of a fixed - income investment to a change in interest rates.

Data through November 2013, released today by S&P Dow Jones Indices and Experian for the S&P / Experian Consumer Credit Default Indices, a comprehensive measure of changes in consumer credit defaults, showed stability in national default rates during the month.

Long positions in the shekel are not looking good according to 2 other measures either: 6 - month momentum and the one - month change in the 10 - year interest rate, see the last 2 columns in the second table.

The velocity of money measures the rate at which money flows through an economy, in other words, how much money changes hands; it has to do with the amount of economic activity associated with a given money supply.

Duration measures how sensitive a bond's price is to changes in interest rates — higher duration bonds experience bigger gains and losses in response to a change in interest rates.

The change in load cell output occurring with time, while under load, and with all environmental conditions and other variables remaining constant; usually measured with Rated Load applied and expressed as a percent of Rated Output over a specific period of time.

Among the measures contained in the HMRC note Changes to tax reliefs following the Scottish Government's Budget2 was confirmation that taxpayers impacted by the introduction of the new starter (19 %) and intermediate (21 %) rates will continue to benefit from Marriage Allowance at the rate of 20 %, worth up to # 238 per year.

The test results will still be used to measure teachers» performance ratings, and a spokesman for the teachers union says until that changes, many of the parents involved in the boycott movement will continue to opt their kids out of the tests.

Researchers can measure annual changes in how the melt rate occurs, for example, or the effects of a single pulse of warm deep - ocean water.

Due to experimental constraints caused by the presence of chamber walls, the change in growth rate that had to be measured was of the order 1 %, which poses a high demand on stability during the experiments, and experiments were repeated up to 100 times in order to obtain a good signal relative to unwanted fluctuations.

In doing so, ROMY will measure minuscule changes in Earth's spin rate and spin axiIn doing so, ROMY will measure minuscule changes in Earth's spin rate and spin axiin Earth's spin rate and spin axis.

Scientific experiments to measure the rate and effects of climate change on plants aren't matching up to what is happening in nature, a new study finds.

By performing experiments in the precisely controlled environment of the CLOUD chamber, the project's scientists can change the concentrations of chemicals involved in nucleation and then measure the rate at which new particles are created with extreme precision.

Earth System Threshold Measure Boundary Current Level Preindustrial Climate Change CO2 Concentration 350 ppm 387 ppm 280 ppm Biodiversity Loss Extinction Rate 10 pm > 100 pm * 0.1 - one pm Nitrogen Cycle N2 Tonnage 35 mmt ** 121 mmt 0 Phosphorous Cycle Level in Ocean 11 mmt 8.5 - 9.5 mmt — 1 mmt Ozone Layer O3 Concentration 276 DU # 283 DU 290 DU Ocean Acidification Aragonite ^ ^ Levels 2.75 2.90 3.44 Freshwater Usage Consumption 4,000 km3 ^ 2,600 km3 415 km3 Land Use Change Cropland Conversion 15 km3 11.7 km3 Low Aerosols Soot Concentration TBD TBD TBD Chemical Pollution TBD TBD TBD TBD * pm = per million ** mmt = millions of metric tons #DU = dobson unit ^ km3 = cubic kilometers ^ ^ Aragonite is a form of calcium carbonate.

To look at the rate of change in working memory in relation to different measures of socioeconomic status, the researchers studied more than three hundred 10 - through 13 - year - olds from urban public and parochial schools over four years.

For the first time, using sophisticated tools to measure skin color, blood flow, and temperature, researchers found that patients on the drug who had a very rapid onset of flushing — redness, pain, swelling, and heat to the face — rated the experience far more harshly than patients whose skin changed gradually, even to the point of extreme redness or change in temperature over time.

The duo allowed leeches to feast on sheep's blood until they were full, measuring both the change in the length of their segments as they fed and the rate at which they spread as they crawled.

In some areas, particularly in Eurasia, climate change — as measured by changes in temperature and precipitation from 21,000 years ago until now — also seems to have influenced extinction rateIn some areas, particularly in Eurasia, climate change — as measured by changes in temperature and precipitation from 21,000 years ago until now — also seems to have influenced extinction ratein Eurasia, climate change — as measured by changes in temperature and precipitation from 21,000 years ago until now — also seems to have influenced extinction ratein temperature and precipitation from 21,000 years ago until now — also seems to have influenced extinction rates.

Many previous studies have focused on measuring psychophysiological metrics, including driver eye movements, muscle activity and changes in heart rate to determine alertness.

Tracking software builds a 3 - D model of the operator's head using infrared lighting, then measures and analyzes changes in head position as well as eye closure rate.

The short string of DNA contained in the mitochondria (mDNA) which accounts for only a small fraction of the total cellular DNAaccumulates mutations at a relatively regular rate and so researchers can use variations in its genes to measure evolutionary changes.

The researchers found that the rates of subclinical atherosclerosis progression, as measured by changes in common carotid artery intima - media thickness or coronary artery calcium, did not differ significantly between men assigned to the testosterone or placebo groups.

The first shows the measured over-subscription rate for the GBT of the past five years, and a predicted over-subscription rate, assuming the average number of hours requested for GBT science does not change in the upcoming three years.

The change in «heart rate» was measured using the highly sensitive electrodes in the microelectrode array.

fMRI is generally thought to be no more or less reliable than the traditional polygraph test, which measures the changes in various physiological parameters — such as heart rate, blood pressure and skin conductance — that can change when someone is lying.

Significantly increased global atrophy rates have not been demonstrated before the clinical (motor) onset of HD in patients with HD compared with healthy controls.3, 11 However, our results suggest that with careful selection of subjects relatively close to motor onset on the basis of their CAG repeat size and age, 20 it should be possible to measure longitudinal changes in global pathology within 5 years of motor onset.

So if the change in body mass predicts a drop in metabolic rate of 100 calories and the measured drop is 150 calories, the extra 50 is the adaptive component.

Oxygen uptake and carbon dioxide production were measured by using a respiratory chamber to assess changes in energy expenditure, respiratory quotient (RQ; CO2 produced / O2 consumed), and carbohydrate and lipid oxidation rates, respectively.

We have shown that, despite their limitations, aggregate measures of non-cognitive skills based on student self - reports provide useful information about students» development, as both levels and year - to - year changes in students» self - ratings are associated with changes in related academic and behavioral outcomes.

Until the measures that are incorporated into the Quality Counts ratings are more clearly tied to education outcomes, we are likely to see continued shifts in rankings that bear little resemblance to actual changes in education quality.

We included administrative data from teacher, parent, and student ratings of local schools; we considered the potential relationship between vote share and test - score changes over the previous two or three years; we examined the deviation of precinct test scores from district means; we looked at changes in the percentage of students who received failing scores on the PACT; we evaluated the relationship between vote share and the percentage change in the percentile scores rather than the raw percentile point changes; and we turned to alternative measures of student achievement, such as SAT scores, exit exams, and graduation rates.

Year 4 Science Assessments Objectives covered: Recognise that living things can be grouped in a variety of ways Explore and use classification keys to help group, identify and name a variety of living things in their local and wider environment Recognise that environments can change and that this can sometimes pose dangers to living things Describe the simple functions of the basic parts of the digestive system in humans Identify the different types of teeth in humans and their simple functions Construct and interpret a variety of food chains, identifying producers, predators and prey Compare and group materials together, according to whether they are solids, liquids or gases Observe that some materials change state when they are heated or cooled, and measure or research the temperature at which this happens in degrees Celsius (°C) Identify the part played by evaporation and condensation in the water cycle and associate the rate of evaporation with temperature Identify how sounds are made, associating some of them with something vibrating Recognise that vibrations from sounds travel through a medium to the ear Find patterns between the pitch of a sound and features of the object that produced it Find patterns between the volume of a sound and the strength of the vibrations that produced it Recognise that sounds get fainter as the distance from the sound source increases Identify common appliances that run on electricity Construct a simple series electrical circuit, identifying and naming its basic parts, including cells, wires, bulbs, switches and buzzers Identify whether or not a lamp will light in a simple series circuit, based on whether or not the lamp is part of a complete loop with a battery Recognise that a switch opens and closes a circuit and associate this with whether or not a lamp lights in a simple series circuit Recognise some common conductors and insulators, and associate metals with being good conductors

We also aim to determine whether this new measure is sensitive to second - to - second changes in children's physiological arousal (e.g., skin conductance, heart rate, movement), as measured using a wearable but non-intrusive autonomic sensing device.

Winner: Woodside Primary Academy, London Woodside was put into special measures by Ofsted in 2012, but changes made under headteacher Shane Tewes involved parents and pupils, and a remarkable turnaround now sees the school rated Outstanding.

California will continue to land at the very bottom of every measure of how well we're preparing our students for the future — graduation rates, social and emotional wellbeing, math and reading achievement — unless we make serious changes to ensure every student has a great teacher, in every subject, every year.

In the latest issue of the New York Review of Books, Christopher Jencks reviews Legacies of the War on Poverty and explains why there is disagreement over the impact of the War on Poverty (and also why it is so difficult to measure changes in the poverty rate over timeIn the latest issue of the New York Review of Books, Christopher Jencks reviews Legacies of the War on Poverty and explains why there is disagreement over the impact of the War on Poverty (and also why it is so difficult to measure changes in the poverty rate over timein the poverty rate over time).

We achieved this sign - on rate even though all participating LEAs will have to implement a bold set of policy and practice changes, including using student growth as one of multiple measures in evaluating and compensating teachers and leaders; denying tenure to teachers who are deemed ineffective as gauged partly by student growth; relinquishing control over their persistently lowest - achieving schools; increasing the number of students who are taught by effective teachers; and, in many cases, opening their doors to more charter schools.