To
measure white matter integrity, researchers used fractional anisotropy (FA), obtained by diffusion tensor imaging (DTI).
Not exact matches
«We're
measuring such variables as prefrontal cortex volume and
white matter integrity.
For the new study, researchers from the University of Pittsburgh Medical Center (UPMC) in Pittsburgh used diffusion tensor imaging (DTI), an MRI technique that
measures the
integrity of
white matter — the brain's signal - transmitting nerve fibers — to see if injuries to the nerves may be the root cause of these post-traumatic depression and anxiety symptoms.
Compared to controls, patients with depression had decreased fractional anisotropy (FA), a
measure of the structural
integrity of
white matter connections, around an area near the deep gray
matter of the brain that is strongly associated with the brain's reward circuit.
«It was illuminating to see the association between
measures of
white matter integrity and important outcomes occurring months to years down the road in our study population.»
«We retrospectively analyzed the data from the DTI sequence to derive
measures of
white matter integrity, which we compared to clinical
measures and subsequent outcome
measures 6 months to 2.5 years after the initial evaluation.»
Here the authors try combining probing
white matter integrity with a MRI
measure of whether the brain has shrunk as a result of disease.
The aims of the study are 1) to investigate differences in the topographic distribution of
white matter integrity between adolescents with IAD and healthy controls without IAD, making no a priori assumptions about the location of possible abnormalities, and 2) to determine whether there was any relationship between
white matter integrity and neurophysiological
measures in IAD subjects.