Noise has traditionally been difficult to study in biology, because most biological techniques, such as
measurement of gene activity, average the output of many cells, erasing individual variability.
Not exact matches
Rao's team used various approaches, including assays
of telomerase
activity,
measurement of cell growth, and
gene expression profiling
of TSY - 1 treated cells, to determine how it acts.
Using chromatin accessibility and
gene expression
measurements, we present clear evidence that lineage specific enhancer dynamics in hematopoiesis is the result
of lineage specific transcription factor
activity.