This is consistent with what's been found
measuring phthalate levels directly in foods.
The researchers will
measure phthalates in the men's urine sample, then perform DNA methylation analyses on sperm cells and look for a statistical association between these measures as well as sperm quality and embryo development.
The measured phthalate levels and AGD were comparable with data from two pregnancy cohort studies in USA.
The National Resources Defense Council
measured phthalates in a variety of air fresheners and found that 80 percent of them contained phthalates.
Urine samples were taken during the last trimester of pregnancy to
measure phthalate content, and the children were followed up with interviews and testing at ages 3, 5, and 7.
Not exact matches
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They
measured 17 metabolites from 8 different
phthalate parent compounds in that sample, then performed DNA methylation analyses on sperm cells to examine statistical associations.
«We plan to
measure eight different
phthalates to examine the father's environmental health impact on a couple's reproductive success, while future aims will also include their child's health,» he adds.
Dr. Swan is senior investigator on this presentation, which provides new information about how
phthalates target a key pregnancy hormone called human chorionic gonadotropin (hCG), which is made by the placenta and can be
measured in the mother's blood and urine.
Researchers analyzed urine samples to
measure concentrations of 13 substances left after the body metabolizes
phthalates.
The women reported their use of feminine hygiene products like tampons, pads, vaginal douches, feminine spray, feminine powder and feminine wipes and had provided urine samples that were
measured for metabolites of
phthalates.
They
measured the levels of
phthalate flowing through the bodies of pregnant women, and then later
measured the size and characteristics of their infant sons» genitals after birth, between ages two months to three years.
Women who were exposed to the highest levels of two common household chemicals — di - n - butyl
phthalate (DnBP) and di - isobutyl
phthalate (DiBP)-- during pregnancy had children whose IQ scores
measured 6 points lower on average than those women whose exposure was reduced.
The study's lead author Pam Factor - Litvak points out that pregnant women in the United States are exposed daily to
phthalate levels that are similar to those
measured in this study.