Sentences with phrase «mechanism of action in»

The mechanism of action in removing * oestrogens from the body is due to the increase * in hydroxyestrone, thereby improving * the 2/16 hydroxyestrone ratio.

Although genistein is a potent in vitro PTK inhibitor, its mechanism of action in vivo is not known.

Its mechanism of action in RA is unknown.

Early observations suggesting that the virus might attack cancer in part by damaging blood vessels that feed tumor growth led the SillaJen team to strike up a collaboration with McDonald, an expert in tumor vasculature, to investigate the virus's mechanism of action in animal models.

«While further studies are planned to dissect more precisely their mechanism of action in the context of brain aging, our preliminary data point at a role in modulating neuroinflammation, but we have not ruled out additional mechanisms.»

The company believes the drug is the first anti-depression drug with a novel mechanism of action in 30 years, and preparations for launch are underway now.

Membrane - anchored plakoglobins have multiple mechanisms of action in Wnt signaling.

Our team is using a combination of cutting - edge proteomics, molecular and cellular biology strategies to uncover new alt - EJ players and decipher their mechanisms of action in cancer.

Curcumin's mechanisms of action in the brain have been studied extensively.

(More and more research attention is being given to mechanisms of action in this area, including regulation of the enzyme NADPH oxidase.)

Scientific investigations have been carried out to corroborate those ancient uses and discover bell pepper's mechanisms of action in order to find modern medicinal applications.

Mechanisms of Action In the brain L - theanine increases dopamine and serotonin production, [4] although one study showed a decrease in serotonin in rats administered theanine.

Most of the proposed mechanisms of actions in these studies involve changes in cell signaling and decreased production of pro-inflammatory cytokines.

Interferons may have multiple mechanisms of action in viral diseases for example modulating cellular and immune functions and impairing virus replication.

In the present study, we have demonstrated that rat pups exposed to DPP - IV inhibitors with different mechanisms of action in the early postnatal period might develop persistent behavioral disorders.

Specifically, Ms. functioning should Lowell's current dissertation project aims have the capacity to to examine early childhood adversity and other mechanisms of action in the understand their own prediction of child maltreatment potential emotions, regulate those in substance - involved mothers.

Not exact matches

You'll want to create tasks for regular communication (weekly check - in emails with «helpers»), ongoing lists for all SEO opportunities, dates for timely opportunities, rating mechanisms for prioritization and a list of actions items for each new opportunity.

«The sale of the PRV provides an important source of non-dilutive capital to support the rapid advancement of our follow on exon skipping candidates and next generation RNA targeted antisense platform,» he said in a statement, referring to the action mechanism used by the company's therapies.

Minoryx harnesses its unique mechanism of action for potential use in X-ALD, a genetic disease characterized by progressive neurologic deterioration with no available pharmacological treatment.

This week in Beijing, Mr. Wang Qishan, vice premier and leader of the Chinese delegation at the fifth Sino - US Strategic Economic Dialogue (SED), a mechanism launched in 2006 to discuss long - term strategic issues between the two countries, called on the US to take swift action to protect Chinese investments in the US.

If through consumer boycotts and other mechanisms publishers and booksellers begin to feel the pinch, it is the pinch of democracy in action.

Disconnected from the mother through a clean mechanism of molecular competition between anti-hormones and hormones, and catapulted toward the network of sewage system through the action of specific stimulators of the uterine myosins, the embryo ends its existence in an unspectacular fashion.

The central thrusts of a reborn reform movement should be stockholder action to effect corporate decision - making, the mobilization of public influence on Congress, the development of improved rating systems, the encouragement of research to support policy - making, and the creation of support mechanisms to encourage and inform creative people working in the media industries.10.

There is no mechanism, and the existence of magic action is both unevidenced and rejected by various physics, starting with thermodynamics in the 19th century.

In light of actual employment practices, the black conservative rhetoric about race - free hiring criteria (usually coupled with a call for dismantling affirmative action mechanisms) does no more than justify actual practices of racial discrimination.

In such an event, democratic institutions become mechanisms of injustice and oppression, thus defying the moral law to which they, like all human institutions and actions, are subject.

The point of central importance in these developments for a philosophy of man is that man - made physical mechanisms are no longer limited to rigid patterns of mechanical action, but are now admitted to the domain of sensitive response, memory, and even of decision - making — activities that traditionally have been thought the exclusive province of minded organisms.

If it is true, as I suggest, that salvation lies in the direction of an Earth organically in-folded upon itself, it is then surely evident that, though a reciprocal mechanism of action and reaction, the vision and prevision of this ultimate end, this outcome of History and of Life, may be made to play an essential part in the building of the future, if only by creating the atmosphere, the psychic field of attraction, without which it will be impossible for Humanity to continue to converge upon itself.

Though formulated by some of the toughest minds in the history of modern philosophy — Hobbes, Locke, Flume, and Adam Smith — this tradition gave rise to what would appear to be the most wildly utopian idea in the history of political thought, namely, that a good society can result from the actions of citizens motivated by self - interest alone when those actions are organized through the proper mechanisms.

If, e.g., as sometimes happens, the man, after a time, more or less, recovers the faculties of which the injury to his brain had deprived him, and that not in consequence of a renewal of the injured part, but in consequence of the inhibited functions being performed by the vicarious action of other parts, the easiest explanation certainly is that, after a time, consciousness constitutes the remaining parts into a mechanism capable of acting as a substitute for the lost parts.

However, the scientific explanation always moves in the direction of showing that mechanisms can produce analogous actions.

The judgment is not a result of the automatic action of some mechanism built into the moral structure of things, but comes directly and personally from Yahweh himself, whose life and power are thus apprehended primarily in history.

I don't believe in gods at all, I am certain that organized religions are a mechanism of control, and I believe that at the beggining, middle, and end of the day we are all responsible for our own lives and actions (which is why it is so important that we humans that actually live and die in this world figure out how to work together).

Establishing adequate mechanisms to safeguard against potential conflicts of interest in nutrition action.

The difference between the two proposed conditions is only their causes, mechanism of action, treatment options, and in the level of evidence that they really exist.

As there is no mechanism, President Abraham Lincoln justified his actions in attacking the Confederacy because they were still a part of a single country.

It is further bolstered by contemporary neuroscience showing that emotions are fundamentally material and the neurochemicals responsible for these observed states can now be specified and described with a high degree of sophistication, although much more will be known in the future about their nature, diversity and mechanisms of action.

Governor Ambode, who spoke at the May Day Rally, held at the Agege Stadium, Lagos, while attributing the industrial harmony and peace in the State to the maturity and responsibility of the labour unions, applauded them for adopting alternative dispute resolution mechanisms rather than resort to industrial actions.

But other political observers saw in the announcement a chance for Cuomo to boost his profile in several national debates — possibly in advance of a presidential run in 2016 — as well as a convenient mechanism to take unlimited contributions for ads that, while not explicitly urging people to vote for Cuomo or anybody else, present a glowing portrayal of his actions.

The NAS finished reviewing the EPA assessment in April, sending back a long list of questions and advising the EPA not to finalize the document until it could show exactly how formaldehyde causes cancer, a biological mechanism known as the «mode of action.»

A study published by scientists at University of Massachusetts Medical School and the University of Alabama at Birmingham provides insight into the mechanism of action of the drug ataluren, which is showing promise in treating Duchenne muscular dystrophy and cystic fibrosis.

(Hons) program, I moved to the Bose Research Institute in Calcutta for an apprenticeship in Anadi Chatterjee's laboratory to work on the mechanism of penicillin action and methicillin resistance in Staphylococcus aureus.

«Understanding the mechanism of action of this peptide will help in translational studies to further assess the potential for this peptide to be used in medicine,» Beales says.

The next objective of the researchers is to decode the action mechanism of TREX2 in the development and maintenance of psoriasis, so as to design new therapeutic strategies for the treatment of this disease.

The team is also testing the resolution of the microfluidic system with other reagents and materials, bringing researchers one step closer to viewing live biological mechanisms in action at the highest levels of resolution possible.

«These findings reveal a unique fulvestrant signaling process involving the increased regulation of hsa - miR - 765 that suppresses the HMGA1 protein as part of the mechanism underlying the tumor suppressor action in prostate cancer.

Perhaps the mechanisms that allow collective action among chimpanzees served as building blocks for the subsequent evolution of even more sophisticated cooperation later in human evolution.»

The authors performed a systematic literature search for data on e-cigarettes» mechanism of action, their emissions, how they are seen by groups of potential users, their efficacy in smoking cessation, and their addiction potential.

These extensive and selective actions of the conditioned stimulus in Aplysia resemble the actions of conditioned fear stimuli in higher mammals and suggest that the functional equivalent of fear occurs in invertebrates and thus may be an adaptive mechanism that is widespread in the animal kingdom.

But a serendipitous discovery may someday give doctors a new countermeasure against the disease: Researchers report in tomorrow's Science that they have identified a possible mechanism of action for «lethal factor» (LF), a toxic protein produced by the anthrax bacillus that is thought to be one of the principal causes of death in infected individuals.