This is important, because oxidative damage is believed to be one of the key
mechanisms behind ageing and many diseases.
Research on lowly creatures such as fruit flies and roundworms is also playing an important part in exposing
the mechanisms behind ageing and, once again, it is free radicals that are implicated as prime suspects.
In this case, he was testing the idea that a buildup of cellular damage caused by oxidation — technically, the chemical removal of electrons from a molecule by highly reactive compounds, such as free radicals — is the main
mechanism behind aging.
Not exact matches
Ron Duman and colleagues at Yale University began their search for a
mechanism behind depression by comparing post-mortem brain samples from 21 people who had been depressed and 18 people of the same
age.
Eric Kandel of Columbia University in New York and colleagues were interested in understanding the
mechanisms behind normal
age - related memory loss.
Included are talks on
mechanisms of
aging in a wide range of established and non-traditional animal models with the key objective to enhance understanding of the basic biology
behind experimental and lifestyle manipulations thought to have direct translational application to human
aging.
The exception is this new research, published March 22 in Cell, which identifies the key cellular
mechanisms behind vascular
aging and the key role it plays on muscle health.