He told the Daily Telegraph: «Our findings illustrate the need to look more carefully at, and to try to explain,
the mechanisms behind these cancer trends, instead of brushing the causal factors under the carpet and focusing only on cures.»
As expressed in this article however, a lot is understood about
the mechanisms behind cancer formation.
The hope is that seeing life in action at this scale will reveal hidden
mechanisms behind cancer and other diseases.
Not exact matches
What has been learned from oncogenes represents the first peep
behind the curtain that for so long has obscured the
mechanisms of
cancer.
Other experts welcome the Dutch result for a second reason as well: It could lead to insights into
mechanisms behind noninherited breast
cancer.
«Major study of genetics of breast
cancer provides clues to
mechanisms behind the disease.»
«Understanding the
mechanism behind this difference may give us new insights into
cancer,» he says.
The phenomenon, known as Warburg effect, is typical for
cancer cells and the
mechanism behind is believed to benefit
cancer cells by switching biochemical engines from energy manufacturing reactions to anabolic reactions, which primarily support growth of the cell size and proliferation.
«BPA is not a recognized carcinogen, and questions surrounding the
mechanism behind the positive correlation of BPA exposure with prostate
cancer have arisen.»
«Increased eye
cancer risk linked to pigmentation genes that dictate eye color: New research identifies genetic
mechanisms behind rare form of melanoma are also associated with genetic risk for skin melanoma.»
For years, attempts have been made to understand the
mechanism behind the proliferation of
cancer cells: they need metabolites to grow and proliferate as much as a vehicle needs gasoline or electricity to move.
Yet as it turns out, the idea of starving
cancer cells turns out to be a key
mechanism behind some of the latest medical treatments for pNET.
The study also may have broader implications for how clinicians approach the development of such treatments and understand
mechanisms behind resistance to treatment in other
cancers.
New ways of using
mechanisms behind certain blood pressure medications may in the future spare some patient groups both discomfort and lifelong concern over
cancer of the esophagus.
New research by scientists at Dana - Farber
Cancer Institute (Dana - Farber) and Brigham and Women's Hospital (BWH) reveals an unexpected
mechanism behind these tumor regressions.
These include, for example, the
mechanisms behind stem - cell development and what happens when normal cellular growth spirals out of control, such as in
cancer.
Klemke, Wang, and their colleagues are involved in research on aspects of the basic biology
behind metastasis — trying to identify the signal transduction
mechanisms that lead to the spread of breast
cancer cells.
One possible explanation for this inconsistency has been explored by researchers at the
Cancer Research UK Cambridge Institute, who have delved into the mechanism behind a weight loss condition, cachexia, which affects many cancer pat
Cancer Research UK Cambridge Institute, who have delved into the
mechanism behind a weight loss condition, cachexia, which affects many
cancer pat
cancer patients.
The understanding of the
mechanisms behind increased survival for prostate
cancer - patients that receives combined therapies will hopefully lead to better and more optimized treatments.
These findings support an unorthodox approach to investigating such
cancers in that epigenetic rather than mutational processes might be the important underlying molecular
mechanism behind these aggressive
cancers.
To understand the selection
mechanism behind mutations, network - based studies were used to estimate the importance of a mutated protein compared to non-mutated ones in signalling and protein — protein interaction networks.10, 11,12,13 Proteins mutated in
cancer were found having a high number of interacting partners (i.e., a high degree of connectivity), which indicates high local importance.10 Mutated proteins are also often found in the centre of the network, in key global positions, as quantified by the number of shortest paths passing through them if all proteins are connected with each other (i.e., they have high betweenness centrality; hereafter called betweenness).11, 12 Mutated proteins also have high clustering coefficients, which means their neighbours are also neighbours of each other.10, 13 Moreover, neighbourhood analysis of mutated proteins have been previously successfully used to predict novel
cancer - related genes.14, 15 However, to the best of our knowledge, no study has concentrated particularly on the topological importance of first neighbours of mutated proteins in
cancer, and their usefulness as drug targets themselves.
Here's a quote from my book
Cancer Cured for even greater detail into the
mechanisms behind Aspirin: