Sentences with phrase «mechanisms behind disease»
The research lines of the Bakkers group include unraveling the genetics of normal cardiac development and body axis formation during development, investigating the molecular mechanisms of heart regeneration in the zebrafish and how this can be compared to heart injury in the mammals, and modeling of human (cardiac) disease in the zebrafish to unravel biological mechanisms behind the disease and to identify new drug targets.
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In contrast, testosterone accelerates the development of nondiabetic chronic renal disease, and in streptozotocin - induced diabetic male rats, decreased testosterone levels and changes of sex hormone levels exacerbated the development of diabetic nephropathy, showing the importance of sex hormones in pathophysiologic mechanisms behind disease progression (334).
«The study provides new insights into evolution and genetic adaptation, and establishes a framework for investigating the biological mechanisms behind disease resistance and adaptation to climate, knowledge that could be vital for protecting honeybees in a rapidly changing world,» says Matthew Webster.
«Major study of genetics of breast cancer provides clues to mechanisms behind the disease.»
A better understanding of the molecular mechanism behind diseases and reduced body function might lead to improved drugs and therapies in the future,» says Åsa Johansson.
However, the molecular mechanism behind the disease remains unclear.
In addition, we performed a preliminary pathway analysis [12] using these data, to examine the feasibility of this type of tool for future investigations to probe for clues to the pathogenetic mechanisms behind these diseases.
Not exact matches
The existence of two mechanisms would make sense for what we know about biology: Salt is necessary for life, but too much salt can kill you, and not just in the sense that excess salt in the diet may be behind some cases of heart disease.
Not long after the IOM report was published, NIH issued its own written assessment, concluding that research has neglected many of the biological factors behind ME / CFS and urging more basic science aimed at teasing out the mechanisms of the disease.
«Mechanisms behind sensory deficits in Parkinson's disease.»
«Our study highlights the sensory aspects of basal ganglia function and presents a new approach to the mechanisms behind the sensory impairments seen in Parkinson's disease,» says Gilad Silberberg, associate professor at Karolinska Institutet's Department of Neuroscience.
Their findings, reported in Nature Communications, may shed light on human lung disease, in particular, the mechanism behind non-familial pulmonary hypertension in patients with conditions such as emphysema and pulmonary fibrosis.
Their findings will contribute to a better understanding of the mechanisms behind inflammatory liver disease caused by hepatitis C viruses and open up new avenues for therapy development.
«Uncovering the biology of a painful and disfiguring pediatric disease: Scientists have identified the biological mechanism behind the painful, potentially lethal, disfiguring Hyaline Fibromatosis Syndrome.»
«We're trying to get at the heart of the mechanism behind neurodegenerative diseases and with this research believe we've found one that seems to be commonly disrupted in many of them, suggesting that similar drugs may work for some or all of these disorders,» says Jeffrey Rothstein, M.D., Ph.D., a professor of neurology and neuroscience, and director of the Brain Science Institute and the Robert Packard Center for ALS Research at the Johns Hopkins University School of Medicine.
A new study finds that two common drugs — an antidepressant and a treatment for Parkinson's disease — can influence moral decisions, a discovery that could help unravel specific mechanisms behind aggression and eventually help researchers design treatments for antisocial behavior.
If we want to treat the disease, we must first understand the underlying mechanism,» says Dr Jenny Björkqvist at the Department of Molecular Medicine and Surgery, Karolinska Institutet, one of the researchers behind the study.
The hope is that seeing life in action at this scale will reveal hidden mechanisms behind cancer and other diseases.
«New mechanism behind Parkinson's disease revealed.»
If comorbid diseases share overlapping molecular networks, researchers could use the networks to understand the biochemical mechanisms behind them.
«In our lab, we investigate the brain mechanisms behind drug addiction — a common and devastating disease with limited treatment options,» explained Christopher Cowan, PhD, director of the Integrative Neurobiology Laboratory at McLean and an associate professor of psychiatry at Harvard Medical School.
Mechanism behind neuron death in motor neurone disease and frontotemporal dementia discovered
This multilevel approach might give further understanding of mechanism behind genes and their relevance in diseases.
Dr. Gan studies the molecular mechanisms behind the loss of functional neurons in neurodegenerative diseases, including Alzheimer's disease and Frontotemporal Dementia.
Fruit flies serve as a good model organism for understanding the molecular mechanisms behind many human diseases — around 75 percent of disease - causing genes are found in the species in a similar form.
Symposia IV: Sympatho - excitatory Mechanisms in Cardiovascular Disease Researchers will discuss the neural mechanisms behind psychogenic cardiovascular disease and the role of inflammatory cells in the progression of cardiovasculaMechanisms in Cardiovascular Disease Researchers will discuss the neural mechanisms behind psychogenic cardiovascular disease and the role of inflammatory cells in the progression of cardiovascular dDisease Researchers will discuss the neural mechanisms behind psychogenic cardiovascular disease and the role of inflammatory cells in the progression of cardiovasculamechanisms behind psychogenic cardiovascular disease and the role of inflammatory cells in the progression of cardiovascular ddisease and the role of inflammatory cells in the progression of cardiovascular diseasedisease.
By understanding the mechanisms behind maternal induced lacto - programming, we can neutralize maternal milk or supplement infants with milk formula to consequently prevent the progression of disease trajectories in the offspring that are related to early life adversities.
And that's the mechanism behind a lot of these neurodegenerative diseases like Alzheimer's and Parkinson's and multiple sclerosis.
«Future research will reveal the molecular mechanisms behind this immediate stress response and elucidate its role in the development of diseases associated with chronic sleep loss,» said Katrin Ackermann, PhD, the study's lead author.
No one has a complete understanding of the mechanisms behind obesity or coronary artery disease.
The exact mechanism behind the hypoglycemic properties of chia is yet to be fully explained; however, studies suggest that the soluble fiber and antioxidants contained in the seeds reduce postprandial glycemia and blood pressure, helping with the prevention and treatment of metabolic diseases, such as hypertension, high cholesterol, and diabetes.
This is important, because oxidative damage is believed to be one of the key mechanisms behind ageing and many diseases.
It is often said that one of the mechanisms behind rice protein, and other plant proteins, reducing the risk of heart related diseases is due to an inhibition of cholesterol absorption.
On average, about 50 % (range, 41 % to 83 %) of dogs diagnosed with MPL have bilateral luxations.14, 15 In 2 studies of cats, the occurrence of bilateral PL was 38 % in one3 and 81 % in the other.2 Concurrent CCL disease in patients diagnosed with PL has been discussed and studied; rates range from 4 % to 41 %.12, 16 The predominant theory behind this occurrence is that CCL ruptures or tears (commonly abbreviated as CCLRs) may result from chronic PL because of malalignment of the extensor mechanism of the stifle and internal rotation of the proximal tibia.
A leading researcher in the Human Genome Project, he and his colleagues are using the findings to explore the molecular mechanisms behind human disease.