Sentences with phrase «mechanisms for this side effect»

There were multiple deaths due to cerebral edema in the JUNO trials, but the mechanisms for this side effect, as well as the optimal therapy, remain «elusive,» he said.

Not exact matches

And insofar as the government is about to «change the rules,» taking the five - year prohibition on license transfer and extending it a further five years... as you change the rules you effect the marketplace, and disrupt the balance that government strives to offer, so I see a refund as a valid mechanism and a cunning tactic for both sides.

It may have to do with Addyi's high pricing (on par with Viagra at $ 26 per pill without an assistance program), its daily intake requirement (unlike Viagra, it adds up to $ 780 per month), its potentially deleterious side effects (low blood pressure and fainting), its restrictions on alcohol consumption (abstinence vs. large quantities not recommended for Viagra patients), a 10 % efficacy rate (whereas Viagra works 50 % of the time compared to a placebo, according to a recent study), and its subtle neurotransmitter - targeting mechanism (contrast that to the obvious hydraulics of Viagra).

Adenosine offers an entirely new mechanism to exploit for potential treatments — one that may come with fewer side effects and less potential for addiction.

Knowledge of this mechanism can provide targets in the search for novel bone - loss therapeutics to treat human osteoporosis with minimal side effects.

«Psychiatry has long struggled with the fact that, while lithium is highly effective for treating bipolar disorder, the narrow therapeutic window and side effect profile often makes lithium both difficult and sometimes dangerous to work with clinically,» said Todd Gould, MD, of the Department of Psychiatry at the University of Maryland, an expert in the mechanisms of lithium and the neurobiology of bipolar disorder.

The new findings that coupling mechanisms and the receptor are important for keeping the balance may explain why common anti-tumor treatments targeting the receptor have heavy side effects for the skin.

Without identifying the precise mechanisms triggering a headache, it's no wonder the medical establishment has had difficulty formulating a strategy for headaches that doesn't come with a long list of potentially severe side effects.

A reciprocal change in lean and fat mass is observed but further studies are needed to determine the exact mechanism of change and the therapeutic doses needed for older men to obtain optimal results with minimum side effects.

Meclizine is an antihistamine and has antiemetic properties.10 In the past 3 years, it has increased in popularity as a treatment for vestibular disease.10 Its use as a treatment for motion sickness in dogs is considered off label, and its exact mechanism of action for the prevention of motion sickness is not understood.10 If used, the recommendation is to administer it 30 to 60 minutes before travel.10 Sedation has been reported as the most common side effect.10

In a free webcast co-presented by Maddie's Fund ® and the Association of Shelter Veterinarians (ASV), Behavioral Pharmacology in Shelter Settings, boarded Veterinary Behaviorist Dr. Sara L. Bennett will help attendees understand common behavioral concerns and diagnoses in sheltered pets and what medications might be most appropriate for these conditions, as well as different classes, mechanisms of action, indications and side effects of those medications.