Sentences with phrase «mechanisms of brain disorders»

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- Collaborative Research in Computational Neuroscience Supports collaborations among computer scientists, engineers, mathematicians, statisticians, theoreticians and experimental neuroscientists, which are imperative to advance our understanding of the nervous system and mechanisms underlying brain disorders and have a significant impact on the theory and design of engineered systems.

The discovery of a new mechanism that controls the way nerve cells in the brain communicate with each other to regulate our learning and long - term memory could have major benefits to understanding how the brain works and what goes wrong in neurodegenerative disorders such as epilepsy and dementia.

«The practice of the Wim Hof Method may lead to tonic changes in autonomous brain mechanisms, a speculation that has implications for managing medical conditions ranging from diseases of the immune system to more intriguingly psychiatric conditions such as mood and anxiety disorders,» said Diwadkar, professor of psychiatry and behavioral neurosciences.

Researchers at Weill Cornell Medical College have uncovered a mechanism that guides the exquisite wiring of neural circuits in a developing brain — gaining unprecedented insight into the faulty circuits that may lead to brain disorders ranging from autism to mental retardation.

«When you match physiologic changes in the brain with behavioral impairment, you can start to understand the biological mechanisms of this disorder, which may help improve diagnosis, and, in time, treatment.»

The Weizmann Institute's Prof. Alon Chen, together with his then PhD student Dr. Orna Issler, investigated the molecular mechanisms of the brain's serotonin system, which, when misregulated, is involved in depression and anxiety disorders.

Metabolic syndrome, a cluster of cardiometabolic conditions, may be a biological mechanism linking posttraumatic stress disorder (PTSD) to structural brain abnormalities, according to a new study in Biological Psychiatry.

By revealing clear and consistent alterations in key brain regions, the findings shed light on the underlying mechanisms of bipolar disorder.

If the new mechanism also operates in the human brain and can be potentiated, this could become of clinical importance not only for stroke patients, but also for replacing neurons which have died, thus restoring function in patients with other disorders such as Parkinson's disease and Huntington's disease,» says Olle Lindvall, Senior Professor of Neurology.

«Understanding the principles and mechanisms involved in neuronal homeostasis may lead to new approaches in the treatment of these and other brain disorders like Alzheimer's disease.»

«We're trying to get at the heart of the mechanism behind neurodegenerative diseases and with this research believe we've found one that seems to be commonly disrupted in many of them, suggesting that similar drugs may work for some or all of these disorders,» says Jeffrey Rothstein, M.D., Ph.D., a professor of neurology and neuroscience, and director of the Brain Science Institute and the Robert Packard Center for ALS Research at the Johns Hopkins University School of Medicine.

However, scientists have struggled to pinpoint neurobiological mechanisms of the disorder, partly due to the lack of sufficient brain scans.

Despite profound sex differences in the expression of social behavior and the incidence of these psychiatric disorders, little is known about how the brain mechanisms underlying these phenomena differ in females and males.

While previous studies have identified disruption to communication channels in these two areas of the brain contribute to symptoms in psychiatric disorders, the mechanisms that lead to these disturbances have been largely unknown, until now.

«This study gives a glimpse into the mechanism by which different mutations within the same gene can cause distinct defects in the brain, and may help to explain how they may contribute to different disorders,» says Guoping Feng, the James W. and Patricia Poitras Professor of Neuroscience at MIT, a member of MIT's McGovern Institute for Brain Research, a member of the Stanley Center for Psychiatric Research at the Broad Institute, and the senior author of the sbrain, and may help to explain how they may contribute to different disorders,» says Guoping Feng, the James W. and Patricia Poitras Professor of Neuroscience at MIT, a member of MIT's McGovern Institute for Brain Research, a member of the Stanley Center for Psychiatric Research at the Broad Institute, and the senior author of the sBrain Research, a member of the Stanley Center for Psychiatric Research at the Broad Institute, and the senior author of the study.

Delving into the uncharted domains of the brain, they hope to uncover the mechanisms underlying brain diseases such as Alzheimer's and Parkinson?s, as well as epilepsy, stroke, and other neurological disorders, and to find ways of preventing or intervening the disease process.

We aim to identify molecular, circuit, and network mechanisms of cognitive dysfunction and to develop novel therapeutic approaches to restore brain functions in AD and related disorders.

Her aim is to understand, at the molecular level, the mechanisms that control communication between the brain, immune system, and blood vessels — with the ultimate goal of designing new therapies that slow, stop, or reverse the progression of a wide range of neurological disorders, such as MS. Recently, Dr. Akassoglou's lab identified how microglia — a type of immune cell that acts as the brain's first line of defense — are activated when fibrinogen enters the brain or spinal cord.

We hope that by understanding the genetic and environmental factors that predispose to mental illnesses, and understanding the mechanisms of disorders within the brain, that we can develop new strategies to better treat, manage, and ultimately to prevent them.

Rony Paz, PhD, director of the Lab for Neural Mechanisms of Learning at the Weizmann Institute of Science, added, «The goal for the alliance is to demonstrate how collaboration can accelerate understanding of the mechanisms involved in brain disorders and translate that learning into care advances for patients and their familiMechanisms of Learning at the Weizmann Institute of Science, added, «The goal for the alliance is to demonstrate how collaboration can accelerate understanding of the mechanisms involved in brain disorders and translate that learning into care advances for patients and their familimechanisms involved in brain disorders and translate that learning into care advances for patients and their families.»

The institute is expected to focus on nervous systems and brain problems, specifically neurodegenerative diseases, sleep disorders, mechanisms of brain repair, and behavioral disorders.

At Weizmann, Dr. Spiegel will be establishing his own independent research group which will attempt to identify the molecular and cellular mechanisms through which experience alters the structure and function of neural circuits in the brain in behaviorally relevant ways and to understand how these processes, when they go awry, might give rise to psychiatric disorders.

Great Expectations: International Collaboration Holds Great Promise for the Future of Psychiatric Care In an unprecedented move, McLean Hospital and Israel's Weizmann Institute of Science have launched an alliance with the goal of demonstrating how collaboration can accelerate understanding of the mechanisms involved in brain disorders, and translating that learning into care advances for patients and their families.

The identification of the genetic mechanisms underlying human - specific brain development during evolution will transform our ability to decipher the pathophysiological mechanisms underlying neurodevelopmental disorders affecting humans such as autism or schizophrenia.

The society has members world wide that study the genetic basis of a wide range of behaviors and brain disorders together with the underlying neuronal mechanisms using diverse species.

His research focuses on normal molecular mechanisms of brain development and genetic perturbations that underlie disorders of human cognitive development, such as in severe autism spectrum disorders.

Dr. Elias and the OCAR primarily focus on understanding why ERP works (e.g., fear tolerance versus fear habituation; the roles of guilt, willingness, and acceptance; patterns of brain activation during exposure; functional connectivity among brain regions), tailoring treatment to the individual (e.g., elucidation of predictors of response and their underlying processes / mechanisms and neural correlates; rigorous diagnostic characterization of obsessive compulsive related disorders), and evaluating innovative treatments and augmentation strategies (e.g., acceptance and commitment therapy; optimization of inhibitory learning; pharmacological augmentation).

The underpinnings of the abnormal relationship between structural and functional connectivity in this and other brain disorders are unknown, and their investigation may provide insight into the underlying pathophysiological mechanisms, and possibly into compensatory mechanisms that may promote recovery of functional connectivity in case of congenital or acquired white matter loss.

Core areas of research at the institute include work on brain - computer interfaces to aid patients with spinal injury and paralysis; innovative advances in computational neuroscience to address behavior and mood disorders; and research into mechanisms of cell death as part of efforts to identify therapies for neurodegenerative diseases that include amyotrophic lateral sclerosis (ALS) and Alzheimer's.

Stroke survivors with spatial neglect are more likely to develop delirium, an acute disorder of attention and cognition, suggesting that these conditions may share a common brain mechanism.

Molecular mechanisms of brain aging and neurodegenerative disorders: Lessons from dietary restriction.

The Biological Actions and Mechanisms of Brain - Derived Neurotrophic Factor in Healthy and Disordered Brains

Antenatal depression may not only alter development of stress - related biological systems in the fetus, but may also increase risk of obstetrical complications.6 Postnatal depression may also be an early life stressor given known associations with lower levels of sensitive, responsive care needed for infants» development of health attachment relationships, emotional regulation skills, interpersonal skills and stress response mechanisms.7 Early life stressors, such as those that might be associated with maternal depression, can influence brain development, which continues at a rapid pace at least for several years after birth.8 Problems in any of these aspects of development may disrupt the earliest stages of socio - emotional and cognitive development, predisposing to the later development of depression or other disorders.