Not exact matches
«We are trying to understand the causes
of aging by linking the
mechanisms that control the oxidation
of proteins at the
cellular level with the
mechanisms that determine the lifespan
of the whole organism,» Apfeld says.
In this case, he was testing the idea that a buildup
of cellular damage caused by oxidation — technically, the chemical removal
of electrons from a molecule by highly reactive compounds, such as free radicals — is the main
mechanism behind
aging.
The investigators suggest that the premature loss
of estrogen caused by the oophorectomy may affect a series
of aging mechanisms at the
cellular and tissue level across the whole body leading to diseases in multiple systems and organs.
A previous study by Segev at the laboratory for research
of molecular and
cellular mechanisms, directed by Prof. Kobi Rosenblum in the Sagol Department
of Neurobiology at the University
of Haifa, found a connection between a genetic condition known to be a risk factor for sporadic Alzheimer's and premature
aging as manifested in ongoing metabolic stress.
Such effects alone could explain why memory seems to falter with
age, without there being any weakening
of the molecular and
cellular mechanisms of memory itself.
MDI Biological Laboratory (ME, USA) scientist Aric Rogers has received a grant
of US$ 455,000 over two years from the National Institute on
Aging, one
of the institutes
of the National Institutes
of Health, for research on the
cellular mechanisms governing longevity.
BAR HARBOR — The MDI Biological Laboratory has announced that Aric Rogers, Ph.D., has received a grant
of $ 455,000 over two years from the National Institute on
Aging (NIA), one
of the institutes
of the National Institutes
of Health, for research on the
cellular mechanisms governing longevity.
Everon is a leader in understanding
cellular mechanisms of aging and translating this knowledge into development
of anti-
aging therapies.
Topics such as the
mechanisms of cell injury in normal and dystrophic muscle, compensatory muscle regeneration and hypertrophy, and the effects
of various therapies or voluntary exercise on muscle repair, satellite cell activation, muscle growth, bone density and
age - related atrophy are examined using a large variety
of cellular, molecular and whole - animal in vivo assays
of function.
As a result we now have an appropriate human cell system with which to address the
mechanisms of telomere regulation during
cellular aging and the early steps
of tumor formation.
Sarcopenia
of aging: underlying
cellular mechanisms and protection by calorie restriction.