Our members work to advance knowledge in the basic
mechanisms of inheritance, from the molecular to the population level.
Darwin was able to establish natural selection, without any understanding of the genetic
mechanisms of inheritance, or the source of novel variation in a population.
The findings, which are reported online ahead of print in the journal Genetics, give important insights into the understanding of chromosomes and
the mechanisms of inheritance.
However, to explain the origin of DNA as
the mechanism of inheritance, evolutionary theory requires that hundreds of millions of small changes must be retained for thousands upon thousands of generations without producing any survival advantage until some point in the dim and distant future when, lo and behold, they suddenly start working together.
As every schoolchild who has been instructed in the rudiments of science now knows, or should know, modern genetics has provided a completely different account of
the mechanism of inheritance, making untenable the blood theory upon which traditional race lore rested.
«New
mechanism of inheritance could advance study of evolution, disease treatment.»
It was not until Gregor Mendel and the start of the 20th century that the genetic
mechanism of inheritance began to be revealed.
In a finding that supports a new
mechanism of inheritance and the leading theory as to the mysterious causative agent of «mad cow» disease and human Creutzfeldt - Jakob disease, researchers at the University of Chicago's Howard Hughes Medical Institute have shown that a defective cell trait can be propagated by a faulty protein, without any DNA or RNA serving as the genetic blueprint.
The disease is thought to be hereditary but the exact
mechanism of inheritance is not yet known.
Unfortunately we do not know
the mechanism of inheritance.
This will be helpful in working out
the mechanism of inheritance.
The mechanism of inheritance of deafness is not known.
An understanding of simple autosomal recessive and dominant patterns, as explained above, can allow the breeder to make better informed decisions (even though we do not yet know
the mechanism of inheritance) and likely avoid future deaf animals without sacrificing a breeding line that has been shaped over many years.
An association between coat color and deafness has been noted in several breeds but the pattern and
mechanism of inheritance is not always the same.
Not exact matches
We have no evidence at all for it and every reason to deny it on the basis
of what we do know about the
mechanisms of reproduction and
inheritance.
Historically, one
of the important reasons to not only allow
inheritances but to specifically favor
inheritances to a single heir to an entire fortune was that gifts and
inheritances were a major
mechanism by which significant amounts
of property were concentrated under a single manager, which allowed for economies
of scale.
«It could be one
of the
mechanisms for genetic
inheritance of disease — a route we haven't thought
of before,» says Spector.
«We are more than our DNA: Discovering a new
mechanism of epigenetic
inheritance.»
In some organisms, the assignment
of a cell to the germ line is caused by an
inheritance - based
mechanism: Before there is even an embryo, the molecular content
of some cells predetermines them to develop as either germ or soma.
«It is essential to understand the dynamics
of cultural
inheritance at different temporal and spatial scales, to uncover the underlying
mechanisms that drive these dynamics, and to shed light on their implications for our current theory
of evolution as well as for our interpretation and predictions regarding human behavior.»
Scientists investigating the
mechanisms of Down Syndrome (DS) have revealed the earliest developmental changes in embryonic stem cells caused by an extra copy
of human chromosome 21 — the aberrant
inheritance of which results in the condition.
Criteria for inclusion include the first mutation to be discovered, high population frequency, distinctive phenotype, historic significance, unusual
mechanism of mutation, unusual pathogenetic
mechanism, and distinctive
inheritance (e.g., dominant with some mutations, recessive with other mutations in the same gene).
The goal
of the research in the Pawlowski lab is to understand the basis
of inheritance in plants by studying the
mechanisms governing chromosome behavior and genetic recombination in meiosis.
It focuses on the
mechanisms underlying the expression and the
inheritance of the effects
of environmental conditions such as traumatic stress in early postnatal life, on behavior and physiology, and their link with diseases in humans.
While this concept
of epigenetic germline
inheritance has long been met with skepticism, evidence in support
of this route
of information transfer is now overwhelming, and some key
mechanisms underlying germline transmission
of acquired information are emerging.
They discovered that blood type A is the most prevalent, with the important exception
of certain pedigreed breeds, such as Devon Rex and British Shorthair, which have an increased percentage with blood type B. Dr. Giger also determined the
inheritance pattern
of feline blood groups and the
mechanism of neonatal isoerythrolysis, making it possible to avoid fading kitten syndrome in at - risk newborn kittens.
Terminus is undone through Republique's extended delivery
mechanism and the burden
of its episodic
inheritance.
From the perspective
of developmental psychopathology it has been proposed that in addition to biological
mechanisms (e.g., genetic
inheritance; Tsuang and Faraone 1990) and stressful contextual factors (e.g., marital conflict; Cummings et al. 2005; Papp et al. 2004), parental psychological problems affect child development via impaired parenting (Goodman and Godlib 1999).