Sentences with phrase «mechanistic analysis of»

Quantum physics has gone well beyond the completely mechanistic analysis of reality.

Unfortunately biology is still trapped in a very mechanistic analysis of living organisms (PE Chaps.

Not exact matches

In the conception of the physical as «acting,» on the other hand, change of other kinds in addition to locomotive change are admitted, so that a mechanistic analysis must accordingly be only of an aspect of physical acting, which means that since it leaves out of account other aspects or features of change or motion, it is an abstraction.

A mechanistic physiologist analyses my sitting at my word processor in terms of light waves hitting my retina from the keyboard and the screen which then set in train chemical and electrical processes in my nerves and brain.

Fourth, disease network analysis ultimately provides a mechanistic basis for defining phenotypic differences among individuals with the same disease through consideration of unique genetic and environmental factors that govern intermediate phenotypes contributing to disease expression.

Using this «Ribotag» approach tissue - specific changes under DR have been measured in muscle, fat, gut, heart, neurons, germline and malpighian tubules, showing a highly tissue specific response upon DR.. We are developing mechanistic models of gene expression regulation and conducting comprehensive bioinformatics analyses on UTRs, promoters and the coding sequences of various elements of differentially regulated genes.

Analysis of Chemical and Biological Features Yields Mechanistic Insights into Drug Side Effects Miquel Duran - Frigola and Patrick Aloy Chemistry and Biology (2013): http://dx.doi.org/10.1016/j.chembiol.2013.03.017

Hypothesis driven approaches to vaccinology can utilise the knowledge gained from mechanistic mouse models and our molecular understanding of intrinsic defects to human cells.5 However, caution is required when extrapolating data from murine models, as there are substantial differences between immune ageing in mice and humans.6 Nevertheless, model systems and ex vivo analyses of molecular alterations in aged human cells have identified multiple changes in the vaccination response with age and the aged immune system in general.

We want to gain comprehensive mechanistic insight into the division of human mitotic cells, provide a biophysical basis to understand nuclear organisation, and establish methods for systems analysis of the first mitotic divisions of mammalian embryos.

Seeing the value of a quantitative, mechanistic framework for rigorous analyses of RNA catalysis truly changed my approach to science forever.

Dr. Cole's project, «Mechanistic Derivation of Germ Line Mutation by Genome - Wide Mouse Tetrad Analysis,» will help define the global patterns of de novo germ line mutations and the frequencies at which such mutations occur in mice, with the long term goal of understanding the molecular mechanisms underlying germ line mutagenesis and developing strategies to prevent or treat disorders caused by such mutations.

We chose to highlight a diverse set of biological processes and experimental systems to make the point that the principles of cross species analysis of basic gene function extend to the study of all human disorders, and can lead to mechanistic understanding of disease pathogenesis and rationale for the development of new therapies.

74/4: 15 Functional analyses of type 2 diabetes - associated loci provides mechanistic insight into genetic susceptibility.

Where is the mechanistic analysis that says that it is the sea ice over the last couple of years (and not SST, or north - south gradients, or strat - trop connections or whatever) that has caused this?

Uses analyses at national and state scales to examine a suite of climatic and intrinsic drivers of continental - scale West Nile virus epidemics, including an empirically derived mechanistic relationship between temperature and transmission potential that accounts for spatial variability in vectors

(2) In my view, there are very likely strong mechanistic links between the outcomes of Bob's analyses (briefly noting that most of his historic data is based on shipboard measurements) and the biophysical effects I am referring - to — especially from the later 20th century to now.

My assumption is that everything in climate is nonlinear and I question the idea that we can somehow transform proxies — without mechanistic analysis — into some some normally distributed essence of climate.

The research aims for mechanistic understanding of the processes important to the decadal modulation of ENSO and tropical Pacific decadal variability through model experiments and observational analysis.