Sentences with phrase «mechanistic details of»
Until the publication of this study, several mechanistic details of how the low - complexity domain of hnRNPA2 worked and how it changed into aggregates in disease were unknown.
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Littleton's lab is now trying to figure out more of the mechanistic details of how complexin controls vesicle release.
Not exact matches
«The depth and breadth of evidence now implicating cow's milk as a cause of Type 1 diabetes is overwhelming, even though the very complex mechanistic details are not yet fully understood,» T. Colin Campbell wrote in «The China Study.»
As researchers gradually gain more insight into the genome's hierarchy of structures, they will get closer to figuring out how this macromolecular wonder works in all of its vastness and mechanistic detail.
Using Escherichia coli (E. coli) as a model host, the framework consists of a coarse - grained but mechanistic description of host physiology that involves dynamic resource partitioning, multi-layered circuit - host coupling, and a detailed kinetic module of exogenous circuits.
Our laboratory and many others have worked toward a detailed mechanistic understanding of some of the major features of Drosophila development.
With the microRNA signatures of mitochondrial function and dysfunction in RPE cells in hand, combined with a detailed mechanistic understanding of how these microRNAs are transferred from cell to cell, we can use small interfering RNAs to target specific microRNAs and block their adverse effects on mitochondria function and their transfer to other RPE cells.
First of all, in terms of mechanistic details — the stuff I'm working on — there will be a huge amount of progress.
In light of these realizations, the long - term scientific goal of the program is to develop a detailed and mechanistic understanding of not just the tumor cell and tumor mutations, but also all the components of the host microenvironment that influence cancer and the response to cancer therapy.
Second, while there is increasing knowledge of the oscillatory mechanisms underpinning basic vision, models of how visual inputs activate meaning lack mechanistic detail.