Not exact matches
Nineteen adult volunteers with and without a history of atopic dermatitis were recruited
into two randomized forearm - controlled
mechanistic studies.
Notophthalmus viridescens, an urodelian amphibian, represents an excellent model organism to
study regenerative processes, but
mechanistic insights
into molecular processes driving regeneration have been hindered by a paucity and poor annotation of coding nucleotide sequences.
Our current
studies therefore, are not only allowing us to investigate discrete interactions that lead to H. pylori - induced neoplasias but also are providing
mechanistic insights
into other malignancies that arise within the context of microbially initiated inflammatory states.
Studying DNA methylation in the window of conception leads also to
mechanistic insights
into the spatio - temporal control of genomic methylation specificity, including components of histone modification and RNA - directed pathways (small and long).
Study designs, both large scale clinical trials as well as smaller mechanistic studies, will take into consideration and take advantage of the heterogeneity of clinical phenotypes in the study de
Study designs, both large scale clinical trials as well as smaller
mechanistic studies, will take
into consideration and take advantage of the heterogeneity of clinical phenotypes in the
study de
study design.
Until the publication of this
study, several
mechanistic details of how the low - complexity domain of hnRNPA2 worked and how it changed
into aggregates in disease were unknown.
However, a large proportion of this
mechanistic evidence is limited to indirect observations and / or has come from rodent
studies requiring translation
into humans.