Sentences with phrase «mechanoelectrical transduction»

Blueberries also stimulate the growth of new nerve cells and facilitate better communication between nerve cells via a process known as transduction.
Q: What were the challenges you encountered in going from materials science to trauma surgery and signal transduction?
at The Scripps Research Institute and the Burnham Institute, and also at the National Institutes of Health, where her studies spanned signal transduction, cell migration, and neuronal development.
My postdoctoral work involved signal transduction pathways that regulate chemotaxis.
In addition, he said, «The broader questions in gene regulation and signal transduction are also fundamental to immunity.»
These findings suggest that the therapeutic protein was able to interact normally with its binding partners among the USH1 molecular complex (the proteins cadherin 23, protocadherin 15, myosin VIIA and harmonin), as required for the mechanoelectrical transduction apparatus of the hair bundle to function correctly.
Among these was the protein VGLUT1, which is essential for signal transduction in specific nerve cells.
Bowen's lab studied several sigma receptor areas, including signal - transduction pathways, novel binding elements (both agonists and antagonists), and clinical applications.
In addition to authoritative insights and collections of reviews, features, and News Focus articles in Science, Science's Signal Transduction Knowledge Environment and the Science of Aging Knowledge Environment will offer special content on drug discovery.
[See also this week's online Science of Aging Knowledge Environment (SAGE KE) and Signal Transduction Knowledge Environment (STKE)-RSB-.
«Dr. Smith, I'm soon going to be leaving the biochemistry program here at Purdue with a Ph.D. involving signal transduction, and I am wondering if you might make a recommendation of some contacts at your company whom I could talk with.
The researchers examined the crystal structure of the complex of SeV C protein and transcription factor STAT1, and found that SeV C protein inhibits the signal transduction pathway of interferon gamma.
It is expected that the molecular mechanisms underlying the inhibition of interferon signal transduction by C proteins would then be fully identified.
«Science Signaling: Research, Teach, and Discover with the Weekly Journal Devoted to Cellular Signaling Transduction» [PDF, 3.5 MB] Nancy Gough, Ph.D., Editor, Science Signaling, AAAS / Science
Noticing that both grants and jobs in that field were few, she identified her most readily transferrable skill: her insight into cellular signal transduction.
Outer membrane proteins have crucial physiological and structural functions, among them nutrient acquisition, secretion, signal transduction, outer membrane biogenesis, and motility.
The H Foundation and a Signal Transduction in Cancer Training Program of the National Cancer Institute supported the research.
«The Cancer Genome Atlas is a really rich and growing database of publicly available data created to help us understand cancer,» said Horvath, who is a program co-leader of the Signal Transduction in Cancer program at the Lurie Cancer Center.
This process is called signal transduction.
SU101 targets the signal transduction activated by a messenger called platelet - derived growth factor, which controls the genes involved in tissue formation and wound healing.
Peter Parker of the Imperial Cancer Research Fund in London says he is delighted that a drug targeting signal transduction is now in trials.
Mutations of the gene Lps selectively impede lipopolysaccharide (LPS) signal transduction in C3H / HeJ and C57BL / 10ScCr mice, rendering them resistant to endotoxin yet highly susceptible to Gram - negative infection.
Instead, as he reported in the journal Cell, that mechanical transduction at Merkel discs initiates primarily in the Merkel cells.
At the end of the project, the transduction efficiency of the newly made retroviral vectors was tested in hematopoietic cells, and here my «old» techniques came in handy.
In 2014, Gu's research team overturned the common assumption that transduction from the mechanical force takes place at the endings of the sensory nerves in Merkel discs.
They regulate signal transduction and indirectly control plant defense mechanisms.
Heterotrimeric guanine nucleotide — binding protein (G protein)-- coupled receptors constitute the largest family of eukaryotic signal transduction proteins that communicate across the membrane.
The scientists would like to investigate how signal transduction is achieved in grasses whose vascular bundles are structured differently in comparison to Arabidopsis which belongs to the Brassicaceae family.
Lorenz Adlung Division of Systems Biology of Signal Transduction, German Cancer Research Center (DKFZ), Heidelberg, Baden - Württemberg, D - 69120, Germany.
In addition to the increased collaboration, the intellectual critical mass existing within the IMCB also helped the learning process through stimulating discussions with seasoned experts in exciting topics such as signal transduction and cell cycle processes.
By functionally linking the signal transduction of melanopsin to the control circuit of the nuclear factor of activated T cells, we have designed a synthetic signaling cascade enabling light - inducible transgene expression in different cell lines grown in culture or bioreactors or implanted into mice.
Surprisingly, the application of larval oral secretions inhibited the transduction of calcium signals to neighboring leaves in the experiment.
FosB is a transcription factor in the brain which, together with other molecules, is involved in so - called signal transduction (transmission of stimuli to the cells), that is to say conveys genetic information between the cells and also determines whether certain genes are activated or not.
«Depression: Evidence of serotonin signal transduction disturbances.»
Epidermal growth factor receptor (EGFR) signal transduction plays a major role in growth, proliferation and differentiation of mammalian cells.
African - American biologist Ernest Everett Just (1883 - 1941) established a unified approach to genetics, cytology, and embryology to support biological research, including signal transduction.
The restructured program's dozen research groups, Karsenti says, will focus on signal transduction, the cytoskeleton, and membrane trafficking.
Recent studies such as ours, however, establish protein phosphatases as positive and essential regulators of signal transduction, with remarkable substrate specificity and coordinated activities.
The isoforms beta ARK - 2 and beta - arrestin - 2 are highly enriched in and localized to the dendritic knobs and cilia of the olfactory receptor neurons where the initial events of olfactory signal transduction occur.
It is a rare autoimmune disease that results in the body producing antibodies against the NMDA receptor, a protein that plays an important role in signal transduction in the brain.
During the early years of my PhD studies, I was very fascinated by the exciting discoveries in the field of signal transduction, in particular how receptor tyrosine kinases are activated to transmit their signals and how protein complexes are formed through defined protein folds (domains) interacting with specific cellular targets.
In 1995, I began graduate studies on signal transduction by growth factors and receptor tyrosine kinases in the laboratory of Graeme Guy at the Institute of Molecular and Cell Biology (IMCB) in Singapore, obtaining my PhD in 2000.
The cells in your body are sensing their environment through signal transduction.
The «Transduction» is a dance performance which focuses on the nature of intramolecular interactions, bringing the dynamics and the flow into the picture.
This reflects the high sensitivity of the method, allowing to detect the signal transduction and propagation, where only minimal conformational (geometric) changes occur.
I studied the process called signal transduction - transmission of the activating mechanical signal from outside the cell, across the cellular membrane, to FAK inside the cell, leading to the activation of the kinase.
This physical link between the cytoskeletons of neighboring cells allows for the generation and transduction of mechanical signals.
Computational biology; use of control and information theory to study signal transduction pathways.
OMC also aims at potentiating the existing Conditional Mutagenesis Facility by implementing novel approaches to attain tissue -, stage - and site - specific transgene expression in mouse mutant strains, mainly through lentiviral vector - mediated transduction of blastocysts.
Signal transduction through the T - lymphocyte CD4 receptor involves the activation of the internal membrane tyrosine - protein kinase p56lck.
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