In the U.S. study,
median plasma levels of certain PFAAs were highest in alligators on Kiawah Island, an Atlantic Ocean barrier island southwest of Charleston, South Carolina, and on Merritt Island in Florida.
Intraperitoneal administration of insulin to control rats and to rats with pituitary stalk transections or with lesions of the
median eminence resulted in increased
plasma adrenocorticotropin (ACTH)
levels.