Sentences with phrase «mediate cytotoxic»

Platelets mediate cytotoxic T lymphocytes - induced liver damage.

Platelets mediate cytotoxic T lymphocyte - induced liver damage.

Not exact matches

Simultaneously, a cell - mediated immunity system also becomes active, deploying cytotoxic T - cells to directly recognize and kill pathogen - infected cells.

Therefore, to overcome chemoresistance mediated by EMT, drug screening efforts have focused on eliminating the mesenchymal subpopulation by searching for drugs with preferential cytotoxic effects on mesenchymal, rather than epithelial HMLE subpopulations [7].

Poliovirus - specific CD4 + Th1 clones with both cytotoxic and helper activity mediate protective humoral immunity against a lethal poliovirus infection in transgenic mice expressing the human poliovirus receptor.

A Marked Reduction in Priming of Cytotoxic CD8 + T Cells Mediated by Stress - Induced Glucocorticoids Involves Multiple Deficiencies in Cross-Presentation by Dendritic Cells.

In addition, studies showed that the elimination of residual leukemia was primarily mediated by donor CD8 + cytotoxic T lymphocytes and NK cells, whereas the inflammatory cytokines that are secreted mainly by CD4 + Th cells have a very limited role in leukemia eradication but contribute significantly to the toxicity of GVHD (55).

If amiodarone HCL toxicity is mediated through TNFR2, and TNFR2 is not sensitive to solTNF, then addition of solTNFα should not be cytotoxic to the NSCs.

Type 1 is IgE mediated; type 2 cytotoxic antibody mediated; type 3 immune - mediated, type 4 cellular mediated.