(4) Accompanying this altered intestinal permeability is an increased activation of mucosal mast cells, the immune cells that
mediate hypersensitivity / allergic reactions.
Drug - Induced Stevens — Johnson Syndrome (SJS) is an immune - complex -
mediated hypersensitivity disorder caused by an adverse allergic reaction to medications.
Not exact matches
Titled «Peripheral
Hypersensitivity to Subthreshold Stimuli Persists after Resolution of Acute Experimental Disc - Herniation Neuropathy and Is
Mediated by Heightened TRPV1 Receptor Expression and Activity,» the study promises to shed light on the basis of neuropathic pain that persists after apparently successful surgery.
Other
hypersensitivity reactions (II, III and IV) are
mediated by other antibody classes, immune cells or cellular components.
The notion that CD4 + T cells might be the pivotal mediators of corneal graft rejection arose from studies demonstrating the close correlation between delayed - type
hypersensitivity (DTH), a classical CD4 + T cell -
mediated immune process, and corneal graft rejection in rodents (10, 11).
She has served as a member and chair of the NIH
Hypersensitivity, Autoimmunity and Immune -
mediated diseases (HAI) study section and is currently a member of NIAID Council.
These antibodies are
mediated by the IgG branch of the immune system (different branch than the one that makes food allergies)- this is known as a Type IV Delayed
Hypersensitivity reaction.
Their food related problems might reflect an adverse additive effect of multiple modest
hypersensitivity reactions
mediated, for instance, by immune complexes promoting autoimmune reactions in the joints.»
There is evidence that interstitial nephritis results mainly from a delayed
hypersensitivity response to NSAID, and nephrotic syndrome results from changes in glomerular permeability
mediated by prostaglandins and other hormones.
Food sensitivities that are more subtle and delayed are
mediated by a different immune complex, Immunoglobulin G (IgG), and are referred to as delayed
hypersensitivity reaction allergies.
Oral allergy syndrome is a type I immediate
hypersensitivity reaction
mediated by IgE induced by sensitization to pollen.
Allergic (
hypersensitivity) and immune -
mediated reactions: Type 1 (acute anaphylaxis): angiodema (especially the head), anaphylaxis (shock) and death; Type 2 (cytolytic): immune -
mediated hemolytic anemia, immune -
mediated thrombocytopenia (suspected only; causality has not been confirmed); Type 3 (immune - complex): cutaneous ischemic vasculopathy associated with rabies vaccine, corneal edema («blue - eye») associated with CAV - 1 vaccine, immune -
mediated disease.
EGC is thought to be immune
mediated, and may occur in response to
hypersensitivities to insect bites (mosquitoes), food allergies, and inhalant allergies.
Common causes of dog ear infection are water trapped in the ear, foreign material (grass awns), yeast, atopy (inhaled seasonal allergy),
hypersensitivity to foods, bacteria, immune
mediated or autoimmune diseases (pemphigus foliaceus) or mites (Otodectes and Demodex).
Mr. Day divides immune
mediated disease into four main groups —
hypersensitivity diseases, autoimmune diseases, immune system neoplasia (the formation of tumors) and immunodeficiency diseases.
In a letter to Veterinary Times during July 1999, veterinarian Lyn Thomson responded, «This would indicate that veterinarians must consider and report the whole range of immune
mediated diseases post vaccination, including flea allergy, atopic dermatitis, dietary
hypersensitivity, contact
hypersensitivity, asthma, autoimmune diseases, lymphoma, lymphoid leukaemia, multiple myeloma, plasmcytoma, hisiiocytoma, thymoma, and immunodeficiency disease.»
ACT - activated clotting time (bleeding disorders) ACTH - adrenocorticotropic hormone (adrenal gland function) Ag - antigen test for proteins specific to a disease causing organism or virus Alb - albumin (liver, kidney and intestinal disorders) Alk - Phos, ALP alkaline phosphatase (liver and adrenal disorders) Allergy Testing intradermal or blood antibody test for allergen
hypersensitivity ALT - alanine aminotransferase (liver disorder) Amyl - amylase enzyme — non specific (pancreatitis) ANA - antinuclear antibody (systemic lupus erythematosus) Anaplasmosis Anaplasma spp. (tick - borne rickettsial disease) APTT - activated partial thromboplastin time (blood clotting ability) AST - aspartate aminotransferase (muscle and liver disorders) Band band cell — type of white blood cell Baso basophil — type of white blood cell Bile Acids digestive acids produced in the liver and stored in the gall bladder (liver function) Bili bilirubin (bile pigment responsible for jaundice from liver disease or RBC destruction) BP - blood pressure measurement BUN - blood urea nitrogen (kidney and liver function) Bx biopsy C & S aerobic / anaerobic bacterial culture and antibiotic sensitivity test (infection, drug selection) Ca +2 calcium ion — unbound calcium (parathyroid gland function) CBC - complete blood count (all circulating cells) Chol cholesterol (liver, thyroid disorders) CK, CPK creatine [phospho] kinase (muscle disease, heart disease) Cl - chloride ion — unbound chloride (hydration, blood pH) CO2 - carbon dioxide (blood pH) Contrast Radiograph x-ray image using injected radiopaque contrast media Cortisol hormone produced by the adrenal glands (adrenal gland function) Coomb's anti- red blood cell antibody test (immune -
mediated hemolytic anemia) Crea creatinine (kidney function) CRT - capillary refill time (blood pressure, tissue perfusion) DTM - dermatophyte test medium (ringworm — dermatophytosis) EEG - electroencephalogram (brain function, epilepsy) Ehrlichia Ehrlichia spp. (tick - borne rickettsial disease) EKG, ECG - electrok [c] ardiogram (electrical heart activity, heart arryhthmia) Eos eosinophil — type of white blood cell Fecal, flotation, direct intestinal parasite exam FeLV Feline Leukemia Virus test FIA Feline Infectious Anemia: aka Feline Hemotrophic Mycoplasma, Haemobartonella felis test FIV Feline Immunodeficiency Virus test Fluorescein Stain fluorescein stain uptake of cornea (corneal ulceration) fT4, fT4ed, freeT4ed thyroxine hormone unbound by protein measured by equilibrium dialysis (thyroid function) GGT gamma - glutamyltranferase (liver disorders) Glob globulin (liver, immune system) Glu blood or urine glucose (diabetes mellitus) Gran granulocytes — subgroup of white blood cells Hb, Hgb hemoglobin — iron rich protein bound to red blood cells that carries oxygen (anemia, red cell mass) HCO3 - bicarbonate ion (blood pH) HCT, PCV, MHCT hematocrit, packed - cell volume, microhematocrit (hemoconcentration, dehydration, anemia) K + potassium ion — unbound potassium (kidney disorders, adrenal gland disorders) Lipa lipase enzyme — non specific (pancreatitis) LYME Borrelia spp. (tick - borne rickettsial disease) Lymph lymphocyte — type of white blood cell MCHC mean corpuscular hemoglobin concentration (anemia, iron deficiency) MCV mean corpuscular volume — average red cell size (anemia, iron deficiency) Mg +2 magnesium ion — unbound magnesium (diabetes, parathyroid function, malnutrition) MHCT, HCT, PCV microhematocrit, hematocrit, packed - cell volume (hemoconcentration, dehydration, anemia) MIC minimum inhibitory concentration — part of the C&S that determines antimicrobial selection Mono monocyte — type of white blood cell MRI magnetic resonance imaging (advanced tissue imaging) Na + sodium ion — unbound sodium (dehydration, adrenal gland disease) nRBC nucleated red blood cell — immature red blood cell (bone marrow damage, lead toxicity) PCV, HCT, MHCT packed - cell volume, hematocrit, microhematocrit (hemoconcentration, dehydration, anemia) PE physical examination pH urine pH (urinary tract infection, urolithiasis) Phos phosphorus (kidney disorders, ketoacidosis, parathyroid function) PLI pancreatic lipase immunoreactivity (pancreatitis) PLT platelet — cells involved in clotting (bleeding disorders) PT prothrombin time (bleeding disorders) PTH parathyroid hormone, parathormone (parathyroid function) Radiograph x-ray image RBC red blood cell count (anemia) REL Rocky Mountain Spotted Fever / Ehrlichia / Lyme combination test Retic reticulocyte — immature red blood cell (regenerative vs. non-regenerative anemia) RMSF Rocky Mountain Spotted Fever SAP serum alkaline phosphatase (liver disorders) Schirmer Tear Test tear production test (keratoconjunctivitis sicca — dry eye,) Seg segmented neutrophil — type of white blood cell USG Urine specific gravity (urine concentration, kidney function) spec cPL specific canine pancreatic lipase (pancreatitis)-- replaces the PLI test spec fPL specific feline pancreatic lipase (pancreatitis)-- replaces the PLI test T4 thyroxine hormone — total (thyroid gland function) TLI trypsin - like immunoreactivity (exocrine pancreatic insufficiency) TP total protein (hydration, liver disorders) TPR temperature / pulse / respirations (physical exam vital signs) Trig triglycerides (fat metabolism, liver disorders) TSH thyroid stimulating hormone (thyroid gland function) UA urinalysis (kidney function, urinary tract infection, diabetes) Urine Cortisol - Crea Ratio urine cortisol - creatine ratio (screening test for adrenal gland disease) Urine Protein - Crea Ratio urine protein - creatinine ratio (kidney disorders) VWF VonWillebrands factor (bleeding disorder) WBC white blood cell count (infection, inflammation, bone marrow suppression)