The common characteristic of all types of SCID is absence of T - cell -
mediated cellular immunity due to a defect in T - cell development.
Not exact matches
antibody -
mediated immunity - protection provided by antibodies (as opposed to
cellular immunity) Also known as «humoral
immunity.»
We will specifically employ
cellular bioassays including the monocyte monolayer assay and antibody - dependent
cellular inhibition assay to determine the role of
cellular effector mechanisms in anti-PfSEA-1
mediated immunity.
Inventors at MUSC have identified a unique human CD4 + T cell population that expresses high levels of surface CD26, termed CD26high T cells, which
mediate durable antitumor
immunity in vivo, and have immediate clinical relevance for designing new vaccines and
cellular therapies.