Intracellular retention of the NKG2D ligand MHC class I chain - related gene A in human melanomas confers immune privilege and prevents NK cell -
mediated cytotoxicity.
FL - CTL assay: fluorolysometric determination of cell -
mediated cytotoxicity using green fluorescent protein and red fluorescent protein expressing target cells.
Not exact matches
In their study, DN T cells displayed allospecific
cytotoxicity in vitro and
mediated tumor allograft rejection in vivo.
This study also demonstrates the utility of baculovirus -
mediated genetic modification; baculoviruses have a large cloning capacity, are easy to produce and also have low
cytotoxicity to transduced cells.
Microvesicle - and exosome -
mediated drug delivery enhances the
cytotoxicity of Paclitaxel in autologous prostate cancer cells.
IFN - α Augments NK -
mediated Antibody - Dependent Cellular
Cytotoxicity (ADCC) of HIV - 1 Infected Autologous CD4 + T Cells Regardless of MHC - I Downregulation.
Tissue inhibitor of metalloproteinase - 1 prevents cytokine -
mediated dysfunction and
cytotoxicity in pancreatic islets and beta - cells.
Trastuzumab directly inhibits the proliferation of HER2 - overexpressing breast cancer cells and induces immune -
mediated killing of target cancer cells through antibody - dependent cellular
cytotoxicity [20].