Sentences with phrase «mediated epigenetic silencing»

Six speakers were ultimately selected to represent the next generation of cancer researchers, including GMI's very own Angela Ting for her work on RNA - mediated epigenetic silencing in human cancers.

Not exact matches

We are focusing on a few key molecular pathways including; 1) Polycomb - mediated epigenetic gene silencing in the tumor initiation, maintenance, and invasion, 2) c - Met (receptor tyrosine kinase) signal transduction pathways in stemness and migration of these tumor cells, 3) Novel mitogenic signaling pathways that are specific to GSCs, and 4) Identification of radio - and chemo - sensitizing pathway to maximize therapeutic efficacy.

Here, through a genome - wide CRISPR - Cas9 - mediated forward genetic screen, we identified MORC2 as an essential gene required for epigenetic silencing by the HUSH complex.