Sentences with phrase «mediated gene inactivation»
Rational design of highly active sgRNAs for CRISPR - Cas9 - mediated gene inactivation.
http://blog.addgene.org/ Not exact matches
The SKIP - e bioinformatics system has been developed to assist researchers in selecting antisense oligonucleotides that can be used as therapeutic agents to restore the production of a functional deleted protein such as for DMD or as tools to study gene function through the inactivation of a protein through nonsense mediated decay.
We have generated new genetic tools for the analysis of in vivo mast cell functions that allow for cell type - specific inactivation («knock out «-RRB- of target genes selectively in mast cells by Cre loxP - mediated recombination.