Sentences with phrase «mediated gene regulation»

Stephane completed his PhD at Cold Spring Harbor Laboratory studying RNA interference mediated gene regulation in Robert Martienssen's Lab.
The team first set out to determine which RBPs were critical in RNA - mediated gene regulation by applying an RNAi screen to mESCs.

Not exact matches

The Lazar lab has been working on HDAC3 for over a decade, focusing on the pivotal role of this enzyme in hormone - mediated regulation of gene expression and metabolism.
Furthermore, if transcriptional regulation of adipose tissue function contributes to adiposity - dependent modulation of insulin sensitivity, blood pressure, and other medically important traits, then the genes that correlate with body mass will be candidates for mediating these responses and warrant further evaluation.
Prolactin - mediated regulation of lipid biosynthesis genes in vivo in the lactating mammary epithelial cell.
His academic research focused on gene regulation and signal transduction mediated by ion channels and G proteins.
Researchers find Nrf2, a stress response gene, to be a pluripotency gene which mediates its effects through regulation of the proteasome
Thus, clock genes may mediate the leptin - dependent sympathetic regulation of bone formation.
With her recent groundbreaking findings in the field of RNA - mediated regulation based on the CRISPR - Cas9 system, E. Charpentier has laid the foundation for the development of a novel, highly versatile and specific genome editing technology that is revolutionizing life sciences research and could open up whole new opportunities in biomedical gene therapies.
268/4: 45 Identifying the transcription factors mediating enhancer — target gene regulation in the human genome.
Toxoplasma gondii TgIST co-opts host chromatin repressors dampening STAT1 - dependent gene regulation and IFN --LCB- gamma -RCB-- mediated host defenses
Conclusion: These findings highlight innovations specifically evolved in platyhelminths presumably associated with novel mechanisms of gene expression regulation mediated by small RNA pathways that differ to what has been classically described in model organisms.
More recently, it has been suggested that the contrasting attributes of gene compactness, GC content and the length of the intronic and intergenic sequences in Hkg and Tsg might be involved in chromatin mediated regulation for maintaining distinct expression patterns in the gene sets [29].
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