Sentences with phrase «mediated hydrolysis»

Not exact matches

Attenuation of excessive 2 - AG clearance by administration of selective monoacylglycerol lipase inhibitors (MAGL is the primary enzyme mediating 2 - AG hydrolysis) potently diminishes withdrawal - related excessive anxiety and related neurochemical events and reduces withdrawal - induced excessive alcohol consumption.

Thus, a dual mechanism including the involvement of ATP hydrolysis and recruitment of other transcription factors (e.g., Sp1) would seem to occur with DDX3 - mediated transcriptional regulation.

Prior studies suggesting that ApoC - III may predominantly affect LPL - mediated TG hydrolysis were based on fractional clearance rates of ApoB in patients lacking ApoC - III and ApoA - I (13) and in vitro studies showing that excess ApoC - III (or ApoC - I) blocks LPL activity in lipid droplets or emulsions possibly due to competition for the lipid - water interface (12, 19).