Sentences with phrase «mediated regulation of gene»
The Lazar lab has been working on HDAC3 for over a decade, focusing on the pivotal role of this enzyme in hormone - mediated regulation of gene expression and metabolism.
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Furthermore, if transcriptional regulation of adipose tissue function contributes to adiposity - dependent modulation of insulin sensitivity, blood pressure, and other medically important traits, then the genes that correlate with body mass will be candidates for mediating these responses and warrant further evaluation.
Prolactin - mediated regulation of lipid biosynthesis genes in vivo in the lactating mammary epithelial cell.
Researchers find Nrf2, a stress response gene, to be a pluripotency gene which mediates its effects through regulation of the proteasome
Thus, clock genes may mediate the leptin - dependent sympathetic regulation of bone formation.
With her recent groundbreaking findings in the field of RNA - mediated regulation based on the CRISPR - Cas9 system, E. Charpentier has laid the foundation for the development of a novel, highly versatile and specific genome editing technology that is revolutionizing life sciences research and could open up whole new opportunities in biomedical gene therapies.
Conclusion: These findings highlight innovations specifically evolved in platyhelminths presumably associated with novel mechanisms of gene expression regulation mediated by small RNA pathways that differ to what has been classically described in model organisms.
More recently, it has been suggested that the contrasting attributes of gene compactness, GC content and the length of the intronic and intergenic sequences in Hkg and Tsg might be involved in chromatin mediated regulation for maintaining distinct expression patterns in the gene sets [29].