Sentences with phrase «mediated synaptic pruning»

Recently, a research team led by Dr. Cynthia A. Lemere of the Ann Romney Center for Neurologic Diseases at Brigham and Women's Hospital utilized C3 - deficient mice, B6; 129S4 - C3tm1Crr / J (003641) to investigate whether the C3 - mediated synaptic pruning mechanisms at work in the developing brain also contribute to cognitive decline in the aging brain.