Sentences with phrase «mediated therapeutic gene»
This was a virus - mediated therapeutic gene to treat X-linked severe combined immunodeficiency.
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We are focusing on a few key molecular pathways including; 1) Polycomb - mediated epigenetic gene silencing in the tumor initiation, maintenance, and invasion, 2) c - Met (receptor tyrosine kinase) signal transduction pathways in stemness and migration of these tumor cells, 3) Novel mitogenic signaling pathways that are specific to GSCs, and 4) Identification of radio - and chemo - sensitizing pathway to maximize therapeutic efficacy.
Therapeutic levels of fetal hemoglobin in erythroid progeny of -LCB- beta -RCB-- thalassemic CD34 + cells following lentiviral vector - mediated gene transfer.
Researchers describe how a new «universal» strategy for CRISPR - Cas9 - mediated gene correction in patient derived stem cells may represent a promising therapeutic option
The SKIP - e bioinformatics system has been developed to assist researchers in selecting antisense oligonucleotides that can be used as therapeutic agents to restore the production of a functional deleted protein such as for DMD or as tools to study gene function through the inactivation of a protein through nonsense mediated decay.