Sentences with phrase «mediates changes in metabolism»
Furthermore, clipping or genetically ablating wings from flies prevented the protective effects of DR on lifespan, demonstrating a critical role for the observed increase in physical activity in determining lifespan upon DR. To further elucidate the mechanisms by which changes in DR mediates changes in metabolism we are identifying and characterizing various tissue specific modulators of fat metabolsm
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This study shows that the effect of mitochondrial dysfunction on nuclear DNA methylation is mediated by changes in methionine and polyamine metabolism.
Age - related changes in the amygdala, hippocampus and frontal cortex, as well as cognitive and behavioral processes mediated by these brain regions have been related to alterations in 5 - HT function, which may occur as a result of disrupted gut - microbiome - dependent metabolism.»