Sentences with phrase «mediating role of family»

Parental problem drinking and adolescent externalizing behaviors: The mediating role of family functioning.

chool and home connections and children» s kindergarten achievement gains: he mediating role of family involvement

Not exact matches

The widespread recognition of the limits of statist solutions for social problems, and of the indispensable role of mediating institutions such as families, churches, and voluntary associations.

The protein encoded by the PIK3C2G gene belongs to the phosphatidylinositol -4,5-bisphosphonate 3 - kinase (PI3K) family, which plays a critical role in cancer.28 Experimental evidence suggests that activation of PI3K signaling enhances production of COX - 2 and PGE2, which results in inhibition of apoptosis in colon cancer cell lines that can be restored with NSAID - mediated blockade of PI3K.29

In 2005, the identification of an activating mutation in JAK2 (the V617F mutation) as a STAT5 - activating and disease - causing genetic alteration in a significant proportion of patients with myeloproliferative neoplasms (MPNs) has emphasized the oncogenic role of the JAK tyrosine kinases in hematologic malignancies.2 — 5 JAK2 is a member of the Janus tyrosine kinase family comprising three other mammalian non-receptor tyrosine kinases (JAK1, JAK3 and TYK2) that associate with cytokine receptors lacking intrinsic kinase activity to mediate cytokine - induced signal transduction and activation of STAT transcription factors.6 All JAKs share a similar protein structure and contain a tyrosine kinase domain at the C - terminus flanked by a catalytically inactive pseudokinase domain with kinase - regulatory activity, by an atypical SH2 domain and by a FERM domain that mediates association to the membrane - proximal region of the cytokine receptors.7, 8 Soon after the discovery of JAK2 V617F, we and others described that activating JAK1 mutations are relatively common in adult patients with T - cell acute lymphoblastic leukemia (ALL) and participate in ALL development allowing for constitutive activation of STAT5.9 — 11 Several STAT5 - activating JAK1 mutations were also reported in AML and breast cancer patients.10

This role is mediated by a protein of the SAPS - domain family involved in S - phase entry.

Key to this model is understanding the role that public schools play, not only in educating our youth, but also in serving as the mediating institution to successfully transition immigrant families into the American way of life, into making American values, culture, norms, and language their own.

This mediating role of early child care, however, paled in comparison to family socioeconomic circumstances.

Family - Friendly Human Resource Practice, Organizational Commitment, and Job Performance among Employees: The Mediating Role of Workplace Spirituality

Relationships among Perceived Social Support, Self - esteem, Parenting Attitudes of Mothers and Children «s Social Competence in Multicultural Families: The Mediating Role of Parenting Attitudes

Other studies examining the mediating role of income include: Elizabeth Thomson, Thomas L. Hanson, and Sara S. McLanahan, «Family Structure and Child Well - Being: Economic Resources vs. Parental Behavior,» Social Forces 73 (1994): 221 — 42; Brown, «Family Structure and Child Well - Being» (see note 7); Osborne, McLanahan and Brooks - Gunn, «Young Children's Behavioral Problems in Married and Cohabiting Families» (see note 9).

Middle Class African American Mothers» Depressive Symptoms Mediate Perceived Discrimination and Reported Child Externalizing Behaviors McNeil, Harris - McKoy, Brantley, Fincham, & Beach (2014) Journal of Child and Family Studies, 23 (8) View Abstract Presents results of a study that explored the effects of perceived discrimination on youth outcomes and examined the potential mediating role of maternal depression.

Mediating new roles, expectations and issues of conflict can help avoid commonly destructive forces between spouses and new family members.

My studies contribute to debates about the uneven change in gender inequalities, the role of family processes in exacerbating inequalities across families, and the relevance of public policies in mediating these processes.

Our research sought to disentangle the influence of collectivism on relationship quality and mate preferences by examining the mediating roles of parental influence and family allocentrism.

Attachment and parenting: The mediating role of work - family balance in Portuguese parents of pre-school children.

Effect of family environment on adolescent compulsive buying: mediating role of self - esteem.

Family - supportive organization perceptions and organizational commitment: the mediating role of work — family conflict and enrichment and partner attiFamily - supportive organization perceptions and organizational commitment: the mediating role of work — family conflict and enrichment and partner attifamily conflict and enrichment and partner attitudes.

A secondary purpose of this study was to test the mediating role of adherence in the relation between diabetes - specific family factors and metabolic control.

[jounal] Caputo, A / 1999 / Family violence and juvenile sex offending: Potential mediating roles of psychopathic traits and negative attitudes toward woman / Criminal Justice and Behavior 26: 338 ~ 356

We examine the influence of family - of - origin quality and past romantic relationships on three specific marital paradigms, as well as the mediating role adult attachment may play in these associations.

While current findings suggest spousal support plays a mediating role in family adaptation, greater understanding of the importance of the marital relationship in families of young children with ASD are needed, including its potential as a protective factor, in successful adaptation.

On the other hand, the mediating role of problematic family - level relationships, such as low coparenting support and high conflict between the parents, has rarely been considered, although coparenting difficulties have been linked with both increased depressive symptoms in parents and increased symptoms in toddlers.