Sentences with phrase «medicine clinical trial studies»

How many of these alternative medicine clinical trial studies do you think are based on manipulated results?

Not exact matches

The Chinese government financed nationwide studies into cockroaches» medical value that, after more than two decades of laboratory investigation and clinical trials, had discovered or confirmed dozens of disease - fighting proteins and biochemical compounds with huge potential value in medicine.

In my experience, there actually are NDs whose care is rooted in science - and evidence - based medicine, and who base their recommendations on scientific studies and clinical trials.

«I've been involved in clinical trials for 30 years,» says the study's lead author Bonnie Ramsey, a professor of pediatrics at the University of Washington School of Medicine in Seattle.

Helen McShane, a Professor in the Nuffield Department of Medicine at the University of Oxfordled the 2013 clinical trial who led the 2013 clinical trial, described the CSU study as «really important.»

In an effort to find out, Stephen P. Juraschek, M.D., Ph.D., research and clinical fellow in general internal medicine at the Johns Hopkins University School of Medicine, and his colleagues used data from the DASH (Dietary Approaches to Stop Hypertension) clinical trial, a widely popular and often - cited study whose results were first published medicine at the Johns Hopkins University School of Medicine, and his colleagues used data from the DASH (Dietary Approaches to Stop Hypertension) clinical trial, a widely popular and often - cited study whose results were first published Medicine, and his colleagues used data from the DASH (Dietary Approaches to Stop Hypertension) clinical trial, a widely popular and often - cited study whose results were first published in 1997.

A one - time intravenous infusion of the high dose of gene therapy extended the survival of patients with spinal muscular atrophy type 1 (SMA1) in a Phase 1 clinical trial, according to a study published in the New England Journal of Medicine.

«Our study shows the significant impact of adding carotid plaque measurement using vascular ultrasound and coronary calcium scoring with CT scan to our conventional assessment for cardiovascular disease,» says Roxana Mehran, MD, the study's co-lead author and Director of Interventional Cardiovascular Research and Clinical Trials at the Zena and Michael A. Weiner Cardiovascular Institute at Mount Sinai Heart at Icahn School of Medicine at Mount Sinai.

In anticipation of targeted medicines, pharmaceutical and biotechnology companies are increasingly performing genetic studies of clinical trial participants in hopes of identifying genetic profiles that predict therapeutic outcomes.

«This vaccine appears to be safe for patients, and elicits a broad anti-tumor immunity — we think it warrants further testing in larger clinical trials,» said study lead author Janos L. Tanyi, MD, an assistant professor of obstetrics and gynecology at Penn Medicine.

Those trials have since been halted, but the Institute of Medicine is setting up a panel to study clinical use of these gene signatures.

«Not only do we believe that high - quality, randomized clinical trials are necessary to determine the safety of the Lariat device for off - label procedures, but our analysis raises broader issues with the FDA 510 (k) clearance protocol for medical devices,» said study senior author Jay Giri, MD, MPH, assistant professor in the Cardiovascular Medicine Division at Penn. «We believe there needs to be a method for reassessing the safety of a device that has been cleared for one use but is being frequently used for a different purpose in real - world practice.»

The documentation ranges across the whole spectrum of drug development: Investigators» brochures provide information on all that is currently known about the medicine and so need periodic updating; accurate and concise protocols are required to ensure that trials are performed effectively; clinical trial reports (generally from phase II and III studies) present the information gathered from the trials; higher level documents provide summaries of efficacy and safety data from clinical trial programmes; expert reports provide critical interpretation of the results; and response documents clarify any points that are not clear to the regulatory agencies or provide additional analyses or supporting data for any items of concern.

Many patients and physicians assume that the safety and effectiveness of newly approved drugs is well understood by the federal Food and Drug Administration (FDA)-- but a new study by researchers at Yale School of Medicine shows that the clinical trials used by the FDA to approve new drugs between 2005 and 2012 vary widely in their thoroughness.

He was part of a Northwestern Medicine and Hines V.A. clinical trial that studied whether repeated stimulation with familiar voices could help repair a coma victim's injured brain networks and spur his recovery.

The supplement they took has yet to be proved in large clinical trials, while scientists who have studied it have been caught in the cross fire between converts, willing to take the supplement on faith and anecdotal evidence alone, and skeptics who look askance at all alternative medicine.

During a conversation this month in his office at Weill Cornell Medicine in New York City, Fine rattled off more dismal stats, like the many failed clinical trials of experimental drugs for glioblastoma; like the paltry increase in life expectancy for people with glioblastoma from 12 months in 1990 to 15 today; like the stupid (in hindsight) assumptions about how glioblastomas grow and how to study them in mice.

Two drugs recently showed promise in clinical trials, and now a study in Science Translational Medicine offers both an unprecedentedly deep explanation of how the disease progresses and introduces another potential therapeutic avenue.

«While not a clinical trial, this study, in stark contrast to prevailing attitudes that views these drugs as harmful, speaks to the public health potential of psychedelic medicine,» says Assoc. Prof. Zach Walsh, the co-director for UBC Okanagan's Centre for the Advancement of Psychological Science and Law.

«Most clinical trials for psychotic disorders are limited to cross-sectional or short - term studies that typically last one year or less,» said Martin T. Strassnig, M.D., lead author of the study and associate professor of Integrated Medical Science in FAU's College of Medicine.

«Recruitment for clinical trials in children with autism is one of the biggest challenges we face in studying potential treatments, and we found that process to be accelerated and streamlined by using existing online communities for enrollment,» said lead author Stephen Bent, associate professor of medicine at UCSF.

Yong, a neuroscientist, initially had the idea to test the acne medicine in an animal model since minocycline has many anti-inflammatory properties that he thought could be useful in treating MS. Soon after obtaining successful research results, in studies also supported by the MS Society of Canada and MSSRF, Yong teamed up with Metz who led the transition into a pilot clinical trial, then a Phase 2, and finally the definitive Phase 3 trial.

In a novel animal study design that mimicked human clinical trials, researchers at University of California, San Diego School of Medicine report that long - term treatment using a small molecule drug that reduces activity of the brain's stress circuitry significantly reduces Alzheimer's disease (AD) neuropathology and prevents onset of cognitive impairment in a mouse model of the neurodegenerative condition.

Apart from the loss of time, money and resources, these failures are also «tragic because we have so little clinical trial information on children to begin with,» says Florence Bourgeois, an assistant professor of pediatrics and emergency medicine at Harvard Medical School, who co-authored the study.

Julia Lewis, MD (Vanderbilt University School of Medicine) and her colleagues in the Collaborative Study Group conducted a 441 - patient randomized clinical trial to test the potential of a compound called ferric citrate to bind phosphorus, increase iron stores, and reduce the usage of IV iron and ESAs.

However, a new study by University of California San Diego School of Medicine researchers suggests that, despite promising results in clinical trials, smoking cessation drugs alone may not be improving the chances of successful quitting among smokers in general.

A new study by researchers from the University of Chicago Medicine, based on a 6 - month clinical trial, finds that use of a CGM is cost - effective for adult patients with type 1 diabetes when compared to daily use of test strips.

Double - blind clinical trials, the gold standard for research studies in medicine, have never been conducted to investigate the effects of marijuana's terpenes or its cannabinoids other than THC.

Icahn School of Medicine at Mount Sinai, is where the CTSN's DCC is based which directs each of its clinical trial's design, methodologies, ethical research concerns, study data, analysis and reporting.

Genetically modified «hunter» T cells successfully migrated to and penetrated a deadly type of brain tumor known as glioblastoma (GBM) in a clinical trial of the new therapy, but the cells triggered an immunosuppressive tumor microenvironment and faced a complex mutational landscape that will need to be overcome to better treat this aggressive cancer, Penn Medicine researchers report in a new study this week in Science Translational Medicine.

In the trial, co-led by Rachael Clark, MD, PhD, associate professor of Dermatology at Harvard Medical School, Alain Rook, MD, professor of Dermatology and director of the Cutaneous Lymphoma Program at Penn Medicine, and Joel M. Gelfand, MD, MSCE, associate professor of Dermatology and medical director of the Clinical Studies Unit at Penn Medicine, twelve patients who had previously undergone an average of six treatments for early stage CTCL were treated with topical resiquimod gel at varying doses and intervals.

The results of the HALT - PKD Clinical Trials Network studies will be published online November 15 in two papers in the New England Journal of Medicine to coincide with presentation at the American Society of Nephrology annual meeting.

Should the results of this study be repeated in the larger Phase III trial, it would lead to a new standard of care for kidney cancer patients, said Dr. Hammers, formerly of Johns Hopkins medical system, who holds the Eugene P. Frenkel, M.D. Scholar in Clinical Medicine at UT Southwestern.

We need studies like this to find out how the two are intertwined and hopefully find the right formula to help prevent Alzheimer's disease,» said Dr. Rong Zhang of UT Southwestern, who oversees the clinical trial and is Director of the Cerebrovascular Laboratory in the Institute for Exercise and Environmental Medicine at Texas Health Presbyterian Hospital Dallas, where the Dallas arm of the study is being carried out.

Helen McShane, a Professor in the Nuffield Department of Medicine at the University of Oxford who led the 2013 clinical trial, described the CSU study as «really important.»

«This is the first human trial of this novel stem cell - based implant, which is designed to replace a single - cell layer that degenerates in patients with dry age - related macular degeneration,» says lead author and surgeon for the study Dr. Amir H. Kashani, assistant professor of clinical ophthalmology at the Keck School of Medicine of USC.

The Wake Forest Institute of Regenerative Medicine (WFIRM) has a unique infrastructure that provides facilities and expertise for translational studies, from basic preclinical findings all the way through Phase 2 clinical trials.

The diabetes drug rosiglitazone has been under intense scrutiny since a 2007 study in the New England Journal of Medicine looked at more than 40 clinical trials and linked the drug's use with increased risk of heart attack and death from heart disease.

In a substudy, review outcomes were also compared across different types of clinical research, based in large part on the designations and definitions derived from a number of sources, including a report by Nathan, 14 the Institute of Medicine, 20 the NIH Director's Panel on Clinical Research, 9 the Association of American Medical Colleges and American Medical Association, 21 and the Agency for Healthcare Research and Quality.22 All 3599 R01 applications involving human subjects that were submitted to NIH for the October 2002 council were categorized into 1 of the following: (1) patient - oriented studies of mechanisms of human disease (bench to bedside); (2) clinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified humanclinical research, based in large part on the designations and definitions derived from a number of sources, including a report by Nathan, 14 the Institute of Medicine, 20 the NIH Director's Panel on Clinical Research, 9 the Association of American Medical Colleges and American Medical Association, 21 and the Agency for Healthcare Research and Quality.22 All 3599 R01 applications involving human subjects that were submitted to NIH for the October 2002 council were categorized into 1 of the following: (1) patient - oriented studies of mechanisms of human disease (bench to bedside); (2) clinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified humanClinical Research, 9 the Association of American Medical Colleges and American Medical Association, 21 and the Agency for Healthcare Research and Quality.22 All 3599 R01 applications involving human subjects that were submitted to NIH for the October 2002 council were categorized into 1 of the following: (1) patient - oriented studies of mechanisms of human disease (bench to bedside); (2) clinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified humanclinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified humanclinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified human tissue.

Capitalizing on our experiences with high - profile clinical trials such as the MedSeq Project and BabySeq Project and our strong relationship with the Laboratory for Molecular Medicine, our group is using a combination of modeling and clinical studies to examine the costs and consequences of integrating genome and exome sequencing into a variety of clinical settings.

If those stop working, patients can still go on to have a total joint replacement, which is also a very effective form of therapy, says study coauthor Brian Feagan, MD, a professor of medicine and the director of the clinical trials unit at the Robarts Research Institute at the University of Western Ontario in Canada.

The topic has fascinated study author Dr. Vinay Prasad, an assistant professor of medicine at the Oregon Health and Science University, ever since he noticed that cancer doctors were tweeting about drugs and clinical trials.

The Foundation for Alternative and Integrative Medicine (FAIM) searches the world for affordable, non-toxic, effective treatments.This is done through site visits, conferences, retrospective studies, clinical trials, and networking to integrate new therapies into practice.

The Effects of L - theanine (Suntheanine ®) on Objective Sleep Quality in Boys with Attention Deficit Hyperactivity Disorder (ADHD): A Randomized, Double - blind, Placebo - controlled Clinical Trial Alternative Medicine Review 2011 (Dec); 16 (4): 348 — 354 ~ FULL TEXT This study demonstrates that 400 mg daily of L - theanine is safe and effective in improving some aspects of sleep quality in boys diagnosed with ADHD.

A veterinary clinical trial is a study conducted on veterinary patients and focused on evaluating the effects of new therapies, medical devices and diagnostic tests for eventual use in veterinary or human medicine.

To improve the quality of experimental designs, execution and reporting of clinical trials and other studies described in articles published by the American Journal of Traditional Chinese Veterinary Medicine (AJTCVM)

The palatability of Clavamox Chewable was established in a clinical trial that studied client - owned dogs at VCA veterinary hospitals across the U.S. and was conducted to a protocol approved by FDA's Center for Veterinary Medicine.

To accomplish our mission, we serve as a «one - stop - shop» for our veterinary faculty, other campus units and study sponsors by providing clinical technical expertise, administrative support and financial oversight for small and large animal clinical trials in multiple disciplines, including (but not limited to) ophthalmology, oncology, neurology, cardiology, dermatology, diagnostic imaging, dentistry, internal medicine, orthopedics and soft tissue surgery.

Researchers at the Veterinary Teaching Hospital and the College of Veterinary Medicine try to answer specific clinical questions about new therapies and drugs through trials and studies.

For more information on our current research studies, please visit Purdue Veterinary Medicine Veterinary Clinical Trials.