Sentences with word «megabase»

B. Co-clustering of differentially methylated promoters with common function across megabases of DNA.

We can routinely make chromosomes in megabase size range.

At the lowest level of resolution, the map widget can display the order and length of genes as they appear in a large (megabase size) section of genomic DNA.

The mutation rates in pediatric tumors ranged from 0.02 mutations per megabase in hepatoblastoma to 0.49 in Burkitt's lymphoma.

D. Methylation dependences across megabases are shown.

We have determined the nucleotide sequence of nearly all of the ∼ 120 - megabase euchromatic portion of theDrosophila genome using a whole - genome shotgun sequencing strategy supported by extensive clone - based sequence and a high - quality bacterial artificial chromosome physical map.

The complete 1.66 - megabase pair genome sequence of an autotrophic archaeon, Methanococcus jannaschii, and its 58 - and 16 - kilobase pair extrachromosomal elements have been determined by whole - genome random sequencing.

The majority of involved promoters participated in multi-gene interaction complexes (often spanning megabases) including promoter - promoter and promoter - enhancer interactions.

Campus Hook «The Official Universal College Social Megabase» Fun site filled with all the variety that is college.

C. On chromosome 19, one of the few megabase regions showing decreased methylation in CPA compared to controls contains one of the two human micro-RNA clusters (scale log2 fold differences top and bottom panels: − 0.2 to 0.2).

Bustamante and Poznik obtained highly accurate sequencing results over a length of about 10 megabases of Y chromosome DNA (or 10 million nucleotides) for each of the 69 individuals.

As the authors put it, these analyses «portray a complex landscape of long - range gene - element connectivity across ranges of hundreds of kilobases to several megabases, including interactions among unrelated genes.»

This enormous, 3.9 - megabase genome contains six genome equivalents of foreign mitochondrial DNA, acquired from green algae, mosses, and other angiosperms.

As part of the international effort to sequence the 17 — billion — base - pair hexaploid bread wheat genome (2n = 6x = 42 chromosomes), we constructed a bacterial artificial chromosome (BAC)-- based integrated physical map of the largest chromosome, 3B, that alone is 995 megabases.

The researchers assembled a 1.57 - million base (megabase) genome of a suspected giant virus they called Klosneuvirus.

In particular, this massive transposon amplification had expanded the genome of a species called the microbat by 460 megabases, more genetic material than there is in a pufferfish.

Here we show that hybridization capture on microarrays can successfully recover more than a megabase of target regions from Neandertal DNA even in the presence of ~ 99.8 % microbial DNA.

After low - complexity filtering and barcode / primer trimming, 11,950,557 sequence reads remained, with each read consisting of 67 nucleotides, for a total of ∼ 800 megabases of sequence.

Claudia presents data around how hESC and somatic cell lines frequently acquire segmental copy number variations in the Megabase - scale, forming a non-clonal or low - grade genetic mosaic.

We present the sequence and analysis of the 11 megabase - sized chromosomes of Trypanosoma brucei.

That Nanopore sequencing has the ability to revolutionize sequencing is recently demonstrated by KeyGene's publication: The megabase - sized fungal genome of Rhizoctonia solani assembled from nanopore reads only.

Collectively, these span 577 megabases and 156 megabases (respectively) of unique sequence (18.7 % and 5.1 % of the genome).

Unfortunately, LOH regions tend to be kilobases or megabases in size, containing dozens or hundreds of genes, and identifying which ones are truly affected in terms of cancer remains challenging.