Undergoing immunotherapy within a month of stereotactic radiosurgery resulted in an improved response to treatment for patients with
melanoma brain metastases.
Not exact matches
«
Brain metastases are a secondary brain tumour, which means they are caused by cancer cells that escape from primary tumours like lung, breast or melanoma, and travel to the brain,» said Mohini Singh, the study's primary author and a PhD candidate in biochemistry at the Michael G. DeGroote School of Medicine at McMa
Brain metastases are a secondary
brain tumour, which means they are caused by cancer cells that escape from primary tumours like lung, breast or melanoma, and travel to the brain,» said Mohini Singh, the study's primary author and a PhD candidate in biochemistry at the Michael G. DeGroote School of Medicine at McMa
brain tumour, which means they are caused by cancer cells that escape from primary tumours like lung, breast or
melanoma, and travel to the
brain,» said Mohini Singh, the study's primary author and a PhD candidate in biochemistry at the Michael G. DeGroote School of Medicine at McMa
brain,» said Mohini Singh, the study's primary author and a PhD candidate in biochemistry at the Michael G. DeGroote School of Medicine at McMaster.
Patients were stratified by number of
brain metastases (1 vs. 2 - 3), primary cancer type (
melanoma vs. other histology) and pre-operative tumor size (less than vs. greater than three centimeters).
«Metastatic
brain tumors — often from lung, breast or skin cancers — are the most commonly observed tumors within the
brain and account for about 40 percent of advanced
melanoma metastases.
Safety and clinical activity of ipilimumab in
melanoma patients with
brain metastases: retrospective analysis of data from a phase 2 trial.
Early results from an ongoing trial suggest that pembrolizumab has promising activity in untreated
melanoma patients with
brain metastases.
It has been suggested to replace the diagnosis - specific graded prognostic assessment (DS - GPA, based on performance status and number of
brain metastases) for patients with primary malignant
melanoma with the new Melanoma -
melanoma with the new
Melanoma -
Melanoma - molGPA.
Furthermore, while it is true that metastatic
melanoma is a systemic disease — and also that mortality is not caused by dermal or subcutaneous lesions but rather by
metastases to the liver,
brain, lung, and other sites — locoregional disease is often disfiguring and painful, and locoregional therapy may provide clinical benefit.