Not exact matches
After more than six years of
research, the
research team led by María Soengas, head of CNIO's
Melanoma Group, showed that RAB7 acts as an orchestra director, determining the fate of melanoma cells: at high concentrations of RAB7, cellular autodigestion is very active, and this allows tumor cells to obtain energy, prevent the accumulation of toxic components and thus divide and proliferate; when RAB7 is reduced, cells use endosomes to recycle metastatic proteins, favouring their dispersal throughout t
Melanoma Group, showed that RAB7 acts as an orchestra director, determining the fate of
melanoma cells: at high concentrations of RAB7, cellular autodigestion is very active, and this allows tumor cells to obtain energy, prevent the accumulation of toxic components and thus divide and proliferate; when RAB7 is reduced, cells use endosomes to recycle metastatic proteins, favouring their dispersal throughout t
melanoma cells: at high concentrations of RAB7, cellular autodigestion is very active, and this allows tumor cells to obtain energy, prevent the accumulation of toxic components and thus divide and proliferate; when RAB7 is reduced, cells use endosomes to recycle metastatic proteins, favouring their dispersal throughout the body.
The work published in Cancer Cell complements previous
research efforts from the CNIO
Melanoma Group, which could lead to the development of novel drugs that selectively target the mechanism of cell autodigestion as a potential therapeutic strategy.
Moreover, many people don't apply the proper amount of sunscreen, forget to reapply and missed to apply on all exposed areas resulting in sunburn and increased risk of
melanoma,» said Reza Ghiasvand, a PhD candidate at The Department of Biostatistics and a member of the
research group «Epidemiological Studies of Lifestyle and Chronic Diseases.»
The second report, identifies the immunotherapy resistance mechanism in
melanoma cells, is from a
group led by Kai Wucherpfennig, MD, PhD, director of Dana - Farber's Center for Cancer Immunotherapy
Research, and Shirley Liu, PhD, of Dana - Farber.
The Society for
Melanoma Research (SMR) is an all - volunteer group of scientists dedicated to finding the mechanisms responsible for melanoma and, consequently, new therapies for this
Melanoma Research (SMR) is an all - volunteer
group of scientists dedicated to finding the mechanisms responsible for
melanoma and, consequently, new therapies for this
melanoma and, consequently, new therapies for this cancer.
Since my strong motivation in cancer
research, I was selected to be part of this amazing
group of young researchers and contribute with my work towards a most extensive knowledge on
melanoma.
BioGenoMEL will be coordinated by the University of Leeds and has already received expressions of interest from 6
research groups with large cohorts of
melanoma patients in Spain, Austria, Sweden and the USA.
This non-profit Consortium was set up in 1997 and is comprised of the majority of
research groups worldwide, working on the genetics of familial
melanoma.
Knowing these facts allows the
research group to determine whether people who have had
melanoma live for different period of time after diagnosis according to their lifestyle.
In 1981, Herlyn became an assistant professor and established a laboratory that is, today, one the largest and best - known
research groups on the study of
melanoma biology.