Sentences with phrase «membrane of ion channels»

DHA is active in the membrane of ion channels in the brain, making it easier for them to change shape and transmit electrical signals, and is involved in serotonin metabolism (reduced serotonin production and / or activity is a key factor in depression).

Not exact matches

The researchers found that puffing activated a mechanosensitive channel protein called TRPV4, which is enriched in the membrane of neuronal axons and allows calcium ions to enter the cell.

It was commissioned by Roderick MacKinnon, who shared the Nobel prize in 2003 for his work describing the structural and mechanistic properties of such channels, which are tunnels that regulate the flow of ions across cellular membranes.

Bound to the cell membrane, Na ± K+ATP ase uses the energy of adenosine triphosphate (ATP) molecules to pump sodium out of the cell and potassium into the cell, maintaining a charge gradient that allows ions to flow through open channels.

Unlike the existing reverse - osmosis membranes responsible for more than half of the world's current water desalination capacity, the new membrane process dehydrates ions as they pass through the membrane channels and removes only select ions, rather than indiscriminately removing all ions.

If the three - dimensional structures of the herb elements are elucidated, and a database of them can be established, it may facilitate computer - assisted imitation of docking between the herb element and physiologically important cell membrane proteins such as receptors, ion channels, and transporters.

The researchers have designed a custom integrated circuit to perform these measurements, in which an artificial cell membrane and ion channel are attached directly to the surface of the amplifier chip.

The OHSU scientists are interested in exploring another area of research focused on a type of ion channel in the membrane of neurons that is activated by serotonin.

(Ion channels are passages through a cell's membrane that allow charged particles, or ions, into or out of the cell.)

They use charge in the form of ions to carry energy and information — ion channels control the flow of ions across cell membranes.

Living systems achieve this functionality with their own version of electronics based on lipid membranes and ion channels and pumps, which act as a kind of «biological transistor.»

Birds, by contrast, seem to be impervious to capsaicin, apparently because they lack the right shape of a receptor — an ion channel — on their mucous membranes.

The binding of positively charged calcium ions in its vicinity opens the channel and allows negatively charged chloride ions to permeate across the membrane.

This small protein molecule contains a loop which fits, like a key in a lock, into the ion channel proteins found on nerve cell membranes, which are used to transport sodium and potassium ions in and out of the cell.

Specifically, the bipolar neurons expressed more genes for membrane receptors and ion channels than non-bipolar cells, particularly those receptors and channels involved in the sending and receiving of calcium signals between cells.

In contrast, the cell membrane that the ion channel passes through is built from a bilayer of lipids, which are a form of fat that repels water - soluble substances.

Ion channels are small openings in the cell membrane of nerves that open and close like doors, in order to allow electrically charged ions to enter or exit.

During his postdoc, Dr. Taraska developed and used novel fluorescence methods to study the structure of ion channels in biological membranes.

Ion channels are proteins found in a cell's membrane, which create tiny openings in the membrane that regulate the movement of specific ions.

It is clear, however, that volatile anesthetics, which are more soluble in lipids than in water, primarily affect the function of ion channel and neurotransmitter receptor proteins in the membranes of nerve cells, which are lipid environments.

Researchers have known for decades that some microorganisms, such as single - celled green algae, have proteins that respond to light by opening a channel in the microbe's membranes, allowing the passage of electrically charged ions (such as calcium and sodium).

In those organs, ion channels in the cell membrane of sensory nerve fibers expand as temperature increases.

«These effects happen at the minute level of potassium, chloride, and other ions moving across the neuron outer membrane via channels and transporters,» Dani said.

«We demonstrated some time ago that a molecule called AAQ is capable of causing nerve cells to become light - sensitive, because it modifies the behavior of ion channels in their surface membranes,» Trauner says.

According to a research team led by Thomas Hund, the key may reside in voltage-gated sodium channels, nanoscopic pores that control the flow of sodium ions across the heart cell membrane.

Nerve cells rely on ion channels and pumps to orchestrate the continual ebb and flow of charged particles across the cell membrane, which enables the electrical signaling that nerves use to communicate.

A team of biophysicists from the State University of New York (S.U.N.Y.) at Buffalo used magnetic nanoparticles to control heat - activated protein gates called ion channels embedded in the membranes of nerve cells, allowing the researchers to stimulate a simple reflex in nematode worms at will.

Whereas in the nematode experiment the researchers targeted nanoparticles to temperature - sensitive ion channels that naturally exist in the membranes of the worms» nerve cells, the scientists inserted the gene for a heat - activated ion channel called TRPV1 into the human and rat cells.

The researchers also found that in nerve cells that detect short sounds, that ability is amplified by electrical properties of the nerve cell membrane's ion channels, which allow the entry and exit of charged chemicals.

The SCN5A protein winds through the membrane of heart muscle cells, forming a channel that opens to let sodium ions flow into the cells.

A key stage in the molecular cascade of memory formation appears to be the opening of membrane channels through which calcium ions flow.

Voltage - dependent potassium ion (K +) channels (Kv channels) conduct K + ions across the cell membrane in response to changes in the membrane voltage, thereby regulating neuronal excitability by modulating the shape and frequency of action potentials.

This particular ion channel transmits electrical impulses by allowing charged particles to cross cell membranes in the presence of ATP, the ubiquitous energy - carrying molecule.

Long QT syndrome is caused by defects in ion channels, proteins that maintain heartbeat by controlling the flow of ions across the membrane of heart cells.

The stretching or compression of these tissues opens ion channels in the nerve membrane, which results in a signal to the brain.

A) Ion channels respond to physiological signals by opening and closing molecular gates that control the flow of ions across the membrane.

Future therapies will have to be based on strategies that act by reducing or increasing the number or activity of specific subtypes of pre - and postsynaptic receptors, transporters, and ion channels, or other membrane molecules at the synapse, and by strategies that exploit the new possibilities offered by stem cell technology and targeted repair.

Calcium channels allow the passage of calcium ions in response to depolarization of the cell membrane.

Ion channels are pore - forming membrane proteins that are present in the membranes of all cells.

Her team is currently examining the ion channels that open and close to allow the flow of ions as electrical impulses pass along the nerve cell membrane.

January 23, 1997 How cells prevent suicide Researchers have shown that a mysterious protein, crucial to the survival of cells throughout the body, is able to form a channel through the internal membranes of cells, and thus may perform the vital function of selectively passing atoms or electrically charged ions between the cell's compartments.

«All of the sudden science led us to study surface membrane proteins, including hormone receptors and ion channels,» says Zheng.

54 % of palmitoylation sites map to synaptic proteins including many GPCRs, receptors / ion channels and peripheral membrane proteins.

His studies, ranging from molecular experiments to clinical trials, have generated comprehensive evidence for the efficacy of omega - 3 in preventing cardiac sudden death and established the mechanism by which omega - 3 fatty acids can reduce cardiac arrhythmia by interacting with membrane ion channels and stabilizing the electrical activity of heart cells.

Ions can not normally pass through the membrane; they rely on protein tunnels (called ion channels) that connect the inside of a neuron to the outside.